Hachicha Anis, Belhaj Ala, Karmeni Nadhir, Slimane Abdelhafidh, Bouali Sofiene, Kallel Jalel
Department of Neurosurgery, Tunisia Faculty of Medicine, National Institute of Neurology Tunis, University of Tunis El Manar, Tunis, Tunisia.
J Craniovertebr Junction Spine. 2021 Jul-Sep;12(3):269-278. doi: 10.4103/jcvjs.jcvjs_64_21. Epub 2021 Sep 8.
Intramedullary tumors are neoformations taking part on the spinal cord, and they are a rare pathology. Due to the rarity of such lesions, clinical studies take years to ensure a decent feedback with a significant number of cases.
Our study is retrospective and descriptive.
We share a Tunisian multicentric experience of 27 years through a retrospective study of 120 cases of spinal cord tumors that have been operated in six different centers.
The clinical, radiological, and histological findings have been analyzed along with postoperative results and tumoral progression so that we could conclude to some factors of prognosis concerning the management of these tumors.
The mean age of our patients is 33.84 years. We had 57 males and 63 females. The most frequent revealing symptom was motor trouble presented as frequent as 77.5% of the patients. Glial tumors were represented in 81 of the cases (67.5%) and nonglial by 39 cases (32.5%). Glial tumors we found were essentially 39 ependymomas and 35 astrocytomas. Surgical resection is key in the management of these lesions; the quality of tumoral resection was a significant factor of disease progression as subtotal resection is correlated to more important progression than total one.
We conclude this work with some statements. In terms of functional results, age is not a significant factor. Presurgical functional state, the histological type, and the extent of surgical resection are the important factors.
髓内肿瘤是发生于脊髓的新生物，是一种罕见的病理学情况。由于此类病变罕见，临床研究需要数年时间才能确保有大量病例的合理反馈。
我们的研究是回顾性和描述性的。
我们通过对在六个不同中心接受手术的120例脊髓肿瘤病例进行回顾性研究，分享了27年的突尼斯多中心经验。
分析了临床、放射学和组织学检查结果以及术后结果和肿瘤进展情况，以便我们能够得出有关这些肿瘤治疗的一些预后因素。
我们患者的平均年龄为33.84岁。男性57例，女性63例。最常见的首发症状是运动障碍，77.5%的患者出现该症状。81例（67.5%）为神经胶质瘤，39例（32.5%）为非神经胶质瘤。我们发现的神经胶质瘤主要是39例室管膜瘤和35例星形细胞瘤。手术切除是这些病变治疗的关键；肿瘤切除质量是疾病进展的一个重要因素，因为次全切除与比全切除更严重的进展相关。
我们以一些陈述结束这项工作。在功能结果方面，年龄不是一个重要因素。术前功能状态、组织学类型和手术切除范围是重要因素。
