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Cytrellis:一种用于无痕皮肤去除的新型微芯技术:三项前瞻性临床试验总结

Cytrellis: A Novel Microcoring Technology for Scarless Skin Removal: Summary of Three Prospective Clinical Trials.

作者信息

Pozner Jason N, Kilmer Suzanne L, Geronemus Roy G, Jack Megan, Burns Jay A, Kaminer Michael S

机构信息

Sanctuary Plastic Surgery, Boca Raton, Fla.

Department of Plastic Surgery, Cleveland Clinic Florida, Weston, Fla.

出版信息

Plast Reconstr Surg Glob Open. 2021 Oct 29;9(10):e3905. doi: 10.1097/GOX.0000000000003905. eCollection 2021 Oct.

DOI:10.1097/GOX.0000000000003905
PMID:34729291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8556055/
Abstract

BACKGROUND

We introduce an innovative and novel technology that achieves scarless skin removal without the use of thermal energy. Microcoring technology (MCT) uses a modified, hollow hypodermic needle to remove skin safely and without a scar. This method is advantageous compared to other fractional devices, given that it has the same benefits as energy-based devices (removal of skin cores without a scar), with the added value of immediate closure along the relaxed skin tension lines, with significantly less thermal energy.

METHODS

Three prospective clinical safety trials analyzing MCT treatment on abdominal and facial skin (short- and long-term) are described.

RESULTS

MCT treatment of human skin resulted in scarless skin removal that was well tolerated by patients. Healing occurred rapidly, with limited side effects. Skin area reduction (skin tightening) and increase in skin thickness were observed long term.

CONCLUSIONS

MCT treatment of human skin is safe and well tolerated. Although further studies on efficacy are required to evaluate the full potential of MCT in skin rejuvenation, early findings such as skin tightening and increase in skin thickness are encouraging.

摘要

背景

我们引入了一种创新的新技术,可在不使用热能的情况下实现无痕皮肤去除。微芯技术(MCT)使用改良的空心皮下注射针安全地去除皮肤且不留疤痕。与其他分次治疗设备相比,该方法具有优势,因为它具有与基于能量的设备相同的益处(无痕去除皮肤芯),另外还具有沿皮肤松弛张力线立即闭合的优点,且热能显著减少。

方法

描述了三项分析MCT对腹部和面部皮肤治疗(短期和长期)的前瞻性临床安全性试验。

结果

MCT治疗人体皮肤可实现无痕皮肤去除,患者耐受性良好。愈合迅速,副作用有限。长期观察到皮肤面积减小(皮肤紧致)和皮肤厚度增加。

结论

MCT治疗人体皮肤安全且耐受性良好。尽管需要进一步研究疗效以评估MCT在皮肤年轻化方面的全部潜力,但诸如皮肤紧致和皮肤厚度增加等早期发现令人鼓舞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/11cd01fd7b37/gox-9-e3905-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/0a5637242c2a/gox-9-e3905-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/fc241accb013/gox-9-e3905-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/f5fc5b80bbfc/gox-9-e3905-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/e4b6322eb006/gox-9-e3905-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/11cd01fd7b37/gox-9-e3905-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/0a5637242c2a/gox-9-e3905-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/fc241accb013/gox-9-e3905-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/f5fc5b80bbfc/gox-9-e3905-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/e4b6322eb006/gox-9-e3905-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af1b/8556055/11cd01fd7b37/gox-9-e3905-g005.jpg

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