Department of Neurosurgery, CHU Tours, 2 Boulevard de Tonnelle, 37000, Tours, France.
Physical Medicine and Rehabilitation Department, CHU de Tours, Tours, France.
Eur Spine J. 2022 Jan;31(1):167-175. doi: 10.1007/s00586-021-07049-y. Epub 2021 Nov 2.
The coronavirus 2019 (COVID-19) pandemic led to a compulsory lockdown of 3 months with strict restrictions. The impact of the COVID-19 pandemic has shown broad repercussions on patients with chronic pain; especially for conditions that present a significant emotional participation such as chronic low back pain (cLBP).
We performed a prospective study on 50 patients. Pre- and 1-month post-lockdown questionnaires such as: the Impact of Event Scale (IES), the Oswestry Disability Index (ODI), the Roland-Morris questionnaire (RMQ) and the visual analogue scale (VAS) for back and leg pain intensity were collected.
The mean time of the evolution of cLBP was 33.04 months (range 5-120 months). Eighteen (36%) patients improved their cLBP (i-cLBP), whereas for 14 (28%) it was worse (w-cLBP). Cox multivariate proportional hazard model identified that MODIC 1 disc disease [OR 19.93, IC95% (2.81-102.13), p = 0.015] and at-home workouts [OR 18.854, IC95% (1.151-204.9), p = 0.040] were good prognosis factors of the improvement of cLBP while subclinical/mild Covid-19 anxiety (IES score < 26) was a poor prognosis factor in improving cLBP [OR 0.21, IC95% (0.001-0.384), p = 0.009]. Furthermore, pre-lockdown benzodiazepine medication [OR 2.554, IC95% (1.20-9.9), p = 0.002] was a prognosis factor of worse cLBP. In contrast, patients with severe Covid-19 anxiety (IES score > 26) significantly improved their cLBP [OR 0.58, IC95% (0.025-0.834), p = 0.01].
Lockdown affected the somatic component of cLBP by decreasing activities and physical measures, whereas the SARS-CoV-2 pandemic spectrum paradoxically improved the psychic and emotional component of cLBP.
2019 年冠状病毒病(COVID-19)大流行导致了为期 3 个月的强制性封锁,实施了严格的限制措施。COVID-19 大流行对慢性疼痛患者产生了广泛影响;特别是对于那些表现出明显情绪参与的疾病,如慢性下腰痛(cLBP)。
我们对 50 名患者进行了前瞻性研究。在封锁前和封锁后 1 个月收集了以下问卷:事件影响量表(IES)、Oswestry 残疾指数(ODI)、Roland-Morris 问卷(RMQ)和背部和腿部疼痛强度的视觉模拟量表(VAS)。
cLBP 的平均病程为 33.04 个月(范围 5-120 个月)。18 名(36%)患者的 cLBP 得到改善(i-cLBP),而 14 名(28%)患者的 cLBP 恶化(w-cLBP)。Cox 多变量比例风险模型确定,MODIC 1 椎间盘疾病[OR 19.93,95%CI(2.81-102.13),p=0.015]和在家锻炼[OR 18.854,95%CI(1.151-204.9),p=0.040]是 cLBP 改善的良好预后因素,而亚临床/轻度 COVID-19 焦虑(IES 评分<26)是 cLBP 改善的不良预后因素[OR 0.21,95%CI(0.001-0.384),p=0.009]。此外,封锁前使用苯二氮䓬类药物[OR 2.554,95%CI(1.20-9.9),p=0.002]是 cLBP 恶化的预后因素。相比之下,COVID-19 严重焦虑(IES 评分>26)的患者显著改善了他们的 cLBP[OR 0.58,95%CI(0.025-0.834),p=0.01]。
封锁通过减少活动和身体措施影响了 cLBP 的躯体成分,而 SARS-CoV-2 大流行谱却奇异地改善了 cLBP 的心理和情绪成分。