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多组分干预对神经认知障碍个体的功能能力及日常生活活动独立性的影响

Contribution of a multicomponent intervention on functional capacity and independence on activities of daily living in individuals with neurocognitive disorder.

作者信息

Borges-Machado Flávia, Barros Duarte, Teixeira Laetitia, Ribeiro Oscar, Carvalho Joana

机构信息

CIAFEL - Research Centre in Physical Activity, Health and Leisure, Faculty of Sports, University of Porto, Rua Dr. Plácido Costa 91, 4200-450, Porto, Portugal.

Faculty of Sports, University of Porto, Porto, Portugal.

出版信息

BMC Geriatr. 2021 Nov 3;21(1):625. doi: 10.1186/s12877-021-02591-2.

Abstract

BACKGROUND

To examine the effects of a 6-month multicomponent (MT) exercise intervention in the functional capacity and ability to independently perform activities of daily living (ADL) of individuals diagnosed with neurocognitive disorder (NCD).

METHODS

A quasi-experimental controlled trial with a parallel design study was conducted in multicentered community-based settings. Forty-three individuals (N Female: 30) were allocated to an exercise group (EG; N: 23; mean 75.09, SD = 5.54 years) or a control group (CG; N:20; mean 81.90, SD = 1.33 years). The EG engaged in a 6-month MT program (60-min sessions, twice a week). Exercise sessions were divided into a warm-up, specific training (e.g., coordination and balance, lower and upper body strength, and aerobics), and cool down. Lower body function, mobility, and gait speed were evaluated through Short Physical Performance Battery (SPPB), Timed-Up and Go test (TUG) and 6-Meter Walk test, respectively. The Barthel Index (BI) was administered to assess individuals' ADL independence. Evaluations were performed before and after the 6-month intervention.

RESULTS

Linear Mixed Models revealed a statistically significant interaction (time X group) effect factor on SPPB (B = 2.33, 95% CI: 1.39-3.28, p < 0.001), TUG (B = - 11.15, 95% CI: - 17.23 - - 5.06, p = 0.001), and 6-Meter Walk test (B = 0.17, 95% CI: 0.08-0.25, p < 0.001). No differences between groups or assessment moments were found in the ability of individuals to independently perform ADL.

CONCLUSIONS

The 6-month MT exercise intervention improves the functional capacity of older adults living with NCD.

TRIAL REGISTRATION

ClinicalTrials.gov - identifier number NCT04095962 ; retrospectively registered on 19 September 2019.

摘要

背景

研究为期6个月的多组分(MT)运动干预对被诊断患有神经认知障碍(NCD)的个体的功能能力和独立进行日常生活活动(ADL)能力的影响。

方法

在多中心社区环境中进行了一项平行设计研究的准实验对照试验。43名个体(女性30名)被分配到运动组(EG;n = 23;平均75.09岁,标准差= 5.54岁)或对照组(CG;n = 20;平均81.90岁,标准差= 1.33岁)。运动组参与了为期6个月的MT计划(每次60分钟,每周两次)。运动课程分为热身、特定训练(如协调与平衡、下肢和上肢力量以及有氧运动)和放松。分别通过简短体能状况量表(SPPB)、计时起立行走测试(TUG)和6米步行测试评估下肢功能、活动能力和步速。采用巴氏指数(BI)评估个体的ADL独立性。在6个月干预前后进行评估。

结果

线性混合模型显示,在SPPB(B = 2.33,95%置信区间:1.39 - 3.28,p < 0.001)、TUG(B = - 11.15,95%置信区间:- 17.23 - - 5.06,p = 0.001)和6米步行测试(B = 0.17,95%置信区间:0.08 - 0.25,p < 0.001)上存在统计学显著的交互作用(时间X组)效应因素。在个体独立进行ADL的能力方面,未发现组间或评估时间点之间存在差异。

结论

为期6个月的MT运动干预可改善患有NCD的老年人的功能能力。

试验注册

ClinicalTrials.gov - 标识符编号NCT04095962;于2019年9月19日进行回顾性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69c8/8564955/bc8743798249/12877_2021_2591_Fig1_HTML.jpg

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