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基于经验模态分解算法的超声图像指导下复方丹参注射液联合硫酸镁对妊娠高血压综合征的影响。

Effects of Compound Danshen Injection Combined with Magnesium Sulfate on Pregnancy-Induced Hypertension Syndrome under the Guidance of Empirical Mode Decomposition Algorithm-Based Ultrasound Image.

机构信息

Department of Obstetrics and Gynecology, The Fourth Hospital of Shijiazhuang, Shijiazhuang 050011, China.

出版信息

J Healthc Eng. 2021 Oct 25;2021:9026223. doi: 10.1155/2021/9026223. eCollection 2021.

DOI:10.1155/2021/9026223
PMID:34733460
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8560243/
Abstract

OBJECTIVE

The study focused on the separation effects of ultrasound blood flow signal detection, based on empirical mode decomposition (EMD) algorithm, and the clinical efficacy of Compound Danshen injection and magnesium sulfate in the treatment of pregnancy-induced hypertension (PIH) syndrome.

METHODS

The empirical mode decomposition (EMD) algorithm was optimized first and compared with other algorithms for the accuracy and stability in separation of blood flow signals. 80 patients with PIH syndrome undergoing ultrasound examination were selected as the research subjects and randomly divided into control group and observation group according to the actual treatment methods. 40 cases in the observation group were treated with Compound Danshen injection + magnesium sulfate, and 40 cases in the control group were treated with magnesium sulfate. After the treatment, the clinical indicators of the two groups of patients were analyzed.

RESULTS

The accuracy and stability in separating blood flow signal of the optimized EMD algorithm were better than those of other algorithms. After treatment, the total effective rate and blood pressure control of the observation group were significantly better than those of the control group, and the incidence of adverse maternal and infant outcomes was significantly lower than that of the control group. After treatment, the endothelin-1 (ET-1), C-reactive protein (CRP), and homocysteine (Hcy) indexes of the two groups of patients decreased significantly, and the decrease level of the observation group was significantly greater than that of the control group (  0.05). The prothrombin time (PT), fibrinogen (FIB), activated partial thromboplastin time (APTT), and plasma thrombin time (TT) levels of the two groups after treatment were better than those before treatment, and the observation group was better than the control group (  0.05).

CONCLUSION

The optimized EMD algorithm is of great value for the separation of ultrasound blood flow signals. For patients with PIH syndrome, Compound Danshen injection combined with magnesium sulfate can be used as a treatment plan, which can improve maternal and infant outcomes; control blood pressure; reduce 24 h urine protein and serum ET-1, Hcy, and CRP levels; and improve coagulation function. It is worthy of promotion.

摘要

目的

本研究基于经验模态分解(EMD)算法,重点研究超声血流信号检测的分离效果,并探讨复方丹参注射液联合硫酸镁治疗妊娠高血压(PIH)综合征的临床疗效。

方法

首先对经验模态分解(EMD)算法进行优化,并与其他算法进行比较,以评估其在血流信号分离中的准确性和稳定性。选择 80 例接受超声检查的 PIH 综合征患者作为研究对象,根据实际治疗方法随机分为对照组和观察组。观察组 40 例采用复方丹参注射液+硫酸镁治疗,对照组 40 例采用硫酸镁治疗。治疗后分析两组患者的临床指标。

结果

优化后的 EMD 算法在血流信号分离的准确性和稳定性方面优于其他算法。治疗后,观察组的总有效率和血压控制明显优于对照组,母婴不良结局的发生率明显低于对照组。治疗后,两组患者的内皮素-1(ET-1)、C 反应蛋白(CRP)和同型半胱氨酸(Hcy)指标均明显下降,观察组下降幅度明显大于对照组(  0.05)。治疗后两组患者的凝血酶原时间(PT)、纤维蛋白原(FIB)、活化部分凝血活酶时间(APTT)和血浆凝血酶时间(TT)水平均优于治疗前,且观察组优于对照组(  0.05)。

结论

优化后的 EMD 算法对超声血流信号的分离具有重要价值。对于 PIH 综合征患者,复方丹参注射液联合硫酸镁可作为治疗方案,可改善母婴结局;控制血压;降低 24 h 尿蛋白和血清 ET-1、Hcy 和 CRP 水平;改善凝血功能。值得推广。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/b4a786620364/JHE2021-9026223.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/4c3914da93fa/JHE2021-9026223.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/d86284c65155/JHE2021-9026223.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/bcc44ca10778/JHE2021-9026223.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/c8125a839560/JHE2021-9026223.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/638ddbccc672/JHE2021-9026223.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/1539becc6aac/JHE2021-9026223.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/b4a786620364/JHE2021-9026223.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/4c3914da93fa/JHE2021-9026223.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/d86284c65155/JHE2021-9026223.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/bcc44ca10778/JHE2021-9026223.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/c8125a839560/JHE2021-9026223.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/638ddbccc672/JHE2021-9026223.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/1539becc6aac/JHE2021-9026223.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ea5/8560243/b4a786620364/JHE2021-9026223.007.jpg

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2
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Taiwan J Obstet Gynecol. 2019 May;58(3):396-400. doi: 10.1016/j.tjog.2018.11.034.
3
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Evid Based Complement Alternat Med. 2022 Jun 25;2022:9192655. doi: 10.1155/2022/9192655. eCollection 2022.
4
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Comput Intell Neurosci. 2022 May 26;2022:7951342. doi: 10.1155/2022/7951342. eCollection 2022.
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Clin Exp Hypertens. 2020;42(1):52-60. doi: 10.1080/10641963.2019.1571599. Epub 2019 Feb 20.
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9
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10
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