Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Biomed Res Int. 2021 Oct 25;2021:3416643. doi: 10.1155/2021/3416643. eCollection 2021.
Pitted keratolysis (PK) is a superficial bacterial infection diagnosed mainly by clinical manifestations. Current data on its dermoscopic and histopathological findings, and the correlation of those findings, are limited.
To evaluate the clinical manifestations, dermoscopic, and histopathological findings of PK and to determine the correlations.
Forty naval cadets with PK and five cadets with normal feet were enrolled this cohort study and provided informed consent. Dermoscopy was independently applied and evaluated by 2 dermatologists. Shave biopsies were performed on 37 patients with PK.
Pits were the most common dermoscopic finding (88.1%). The dermoscope had more sensitivity for the detection of PK than the naked eye examinations. Apart from the pits and the presence of bacteria, the most common histopathological finding for PK was color alteration of keratin. The presence of bacteria correlated with interrupted dermatoglyphic lines and the color alteration of keratin. Moreover, the presence of bacteria at the base of pits was related to worse treatment outcomes.
Dermoscopy is a useful tool for PK diagnosis. Color alteration of keratin is another histopathological finding for PK. The presence of bacteria is associated with worse treatment outcomes.
窝状角质松解症（PK）是一种主要通过临床表现诊断的浅表细菌性感染。目前关于其皮肤镜和组织病理学表现及其相关性的数据有限。
评估 PK 的临床表现、皮肤镜和组织病理学表现，并确定其相关性。
本队列研究纳入了 40 名患有 PK 的海军学员和 5 名足部正常的学员，并获得了他们的知情同意。由 2 名皮肤科医生独立进行皮肤镜检查并进行评估。对 37 名 PK 患者进行了削刮活检。
凹坑是最常见的皮肤镜表现（88.1%）。与肉眼检查相比，皮肤镜对 PK 的检测更敏感。除了凹坑和细菌存在外，PK 最常见的组织病理学表现是角蛋白颜色改变。细菌的存在与中断的皮纹和角蛋白颜色改变相关。此外，凹坑底部存在细菌与治疗效果较差相关。
皮肤镜是 PK 诊断的有用工具。角蛋白颜色改变是 PK 的另一种组织病理学表现。细菌的存在与较差的治疗效果相关。
