Department of Science, Prostate Cancer Foundation, Santa Monica, California, USA.
Department of Oncology, Johns Hopkins University School of Medicine and The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
Prostate. 2022 Feb;82(2):169-181. doi: 10.1002/pros.24262. Epub 2021 Nov 3.
The 2021 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, "Prostate Cancer Research in the 21st Century," was held virtually, from June 24-25, 2021.
The CHPCA Meeting is organized by the Prostate Cancer Foundation as a unique discussion-oriented meeting focusing on critical topics in prostate cancer research envisioned to bridge the next major advances in prostate cancer biology and treatment. The 2021 CHPCA Meeting was virtually attended by 89 investigators and included 31 talks over nine sessions.
Major topic areas discussed at the meeting included: cancer genomics and sequencing, functional genomic approaches to studying mediators of plasticity, emerging signaling pathways in metastatic castration resistant prostate cancer, Wnt signaling biology and the challenges of targeted therapy, clonal hematopoiesis, neuroendocrine cell plasticity and antitumor immunity, cancer immunotherapy and its synergizers, and imaging the tumor microenvironment and metabolism.
This meeting report summarizes the research presented at the 2021 CHPCA Meeting. We hope that publication of this knowledge will accelerate new understandings and the development of new biomarkers and treatments for prostate cancer.
2021 年考菲-霍尔顿前列腺癌学会（CHPCA）会议“21 世纪前列腺癌研究”于 2021 年 6 月 24 日至 25 日以虚拟方式举行。
CHPCA 会议由前列腺癌基金会组织，是一场独特的以讨论为导向的会议，重点关注前列腺癌研究中的关键议题，旨在弥合前列腺癌生物学和治疗方面的下一个重大进展。2021 年 CHPCA 会议有 89 名研究人员以虚拟方式参加，共包括九个环节的 31 个报告。
会议讨论的主要议题包括：癌症基因组学和测序、研究可塑性介质的功能基因组方法、转移性去势抵抗性前列腺癌中的新兴信号通路、Wnt 信号生物学和靶向治疗的挑战、克隆性造血、神经内分泌细胞可塑性和抗肿瘤免疫、癌症免疫治疗及其协同剂、以及肿瘤微环境和代谢的成像。
本会议报告总结了 2021 年 CHPCA 会议上提交的研究。我们希望发表这些知识将加速对前列腺癌的新认识以及新的生物标志物和治疗方法的发展。
