Department of Experimental and Clinical Medicine, University of Florence, Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
Int Braz J Urol. 2022 Jan-Feb;48(1):200-201. doi: 10.1590/S1677-5538.IBJU.2021.0455.
: The expansion of technology is leading to a paradigm shift in several urological fields (1, 2). In particular, the adoption of lasers within the surgical treatment of patients with benign prostatic hyperplasia (BPH) is considered one of the most relevant innovations (3-5). In this video, we aimed to report our experience with holmium laser for the ablation of the prostate (HoLAP) in patients with obstructive lower urinary tract symptoms (LUTS) due to BPH.
: From 2018 to 2020, 10 patients with obstructive LUTS secondary to BPH were treated at our Institution with HoLAP (120W Holmium laser Lumenis with Moses technology). Main inclusion criteria were: 1) International Prostate Symptom Score ≥12; 2) prostate volume ≤65mL, 3) maximal flow rate (Qmax) ≤15ml/s at preoperative non-invasive uroflowmetry.
: Mean patient age was 65 (range: 59-72) years. Preoperative mean prostate volume was 50 (range: 35-65) mL. Mean operative time was 66 (range: 45-85) minutes with a mean laser time/operative time ratio of 0.51 (range: 0.44-0.60). Voiding symptoms, Qmax and post voiding residual were significantly improved after 3 and 12 months (all p <0.05). No postoperative urinary incontinence was detected.
: The present findings suggest that HoLAP is a slightly time-spending procedure, thus its use should be limited to prostate volume <70-80mL. However, no postoperative complications were recorded at all. This technique showed to be a safe option in patients with low-intermediate prostate volume, also in patients whose antiaggregant/anticoagulant therapy is maintained.
技术的发展正在导致几个泌尿外科领域发生范式转变(1,2)。特别是,在良性前列腺增生(BPH)患者的手术治疗中采用激光被认为是最相关的创新之一(3-5)。在这个视频中,我们旨在报告我们在经尿道前列腺钬激光消融术(HoLAP)治疗因 BPH 引起的梗阻性下尿路症状(LUTS)患者方面的经验。
从 2018 年到 2020 年,我们机构对 10 例因 BPH 引起的梗阻性 LUTS 患者采用 HoLAP(120W 钬激光 Lumenis 联合 Moses 技术)进行治疗。主要纳入标准为:1)国际前列腺症状评分≥12;2)前列腺体积≤65ml;3)术前非侵入性尿流率检查时最大尿流率(Qmax)≤15ml/s。
患者平均年龄为 65 岁(范围:59-72 岁)。术前平均前列腺体积为 50ml(范围:35-65ml)。平均手术时间为 66 分钟(范围:45-85 分钟),激光时间与手术时间的比值平均为 0.51(范围:0.44-0.60)。术后 3 个月和 12 个月时排尿症状、Qmax 和剩余尿量均显著改善(均 p<0.05)。未发现术后尿失禁。
目前的研究结果表明,HoLAP 是一种耗时较长的手术,因此应将其使用限制在前列腺体积<70-80ml 的患者中。然而,术后并未出现任何并发症。对于前列腺体积较低的患者,尤其是那些需要维持抗血小板/抗凝治疗的患者,该技术是一种安全的选择。