Dr. Cohen is from the Department of Dermatology, Florida International University Herbert Wertheim College of Medicine, Miami. Drs. Farahi, Brodsky, High, and Hugh are from the Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora. Dr. High also is from the Department of Dermatopathology.
Cutis. 2021 Aug;108(2):E28-E31. doi: 10.12788/cutis.0341.
Plasma cell cheilitis (PCC) is an uncommon condition characterized by mature plasma cell infiltration of the dermis of the mucosal lip. The condition often presents as a red-brown patch or plaque on the lower lip in older individuals that can progress to erosions and edema. Diagnosis can be delayed because clinical findings are nonspecific and can mimic neoplastic, infectious, and inflammatory conditions. We describe a patient with PCC who presented to our institution via teledermatology. Findings were equivocal on 2 early biopsies until the presentation evolved to dramatic ulceration and necrosis, which prompted a third biopsy that was diagnostic for PCC. Empiric therapy with a class I topical corticosteroid was successful.
浆细胞性唇炎（PCC）是一种罕见的疾病，其特征是成熟浆细胞浸润粘膜唇的真皮。该疾病常以上唇的红棕色斑块或斑块形式出现在老年患者中，并可进展为糜烂和水肿。由于临床表现不具特异性，且可模拟肿瘤、感染和炎症性疾病，因此可能会延迟诊断。我们描述了一位通过远程皮肤病学就诊于我院的 PCC 患者。在出现戏剧性的溃疡和坏死之前，前两次活检的结果均不确定，随后进行了第三次活检，诊断为 PCC。经验性地使用 I 类局部皮质类固醇治疗取得了成功。
