Dos Santos Harim Tavares, Cunha John Lennon Silva, Santana Lucas Alves Mota, Trento Cleverson Luciano, Marquetti Antônio Carlos, de Albuquerque-Júnior Ricardo Luiz Cavalcanti, de Sousa Sílvia Ferreira
Federal University of Sergipe (UFS), Department of Dentistry, Biological Sciences and Health Center. Aracaju, SE, Brazil.
Tiradentes University, Laboratory of Morphology and Experimental Pathology, Institute of Technology and Research. Aracaju, SE, Brazil.
Autops Case Rep. 2019 Mar 22;9(2):e2018075. doi: 10.4322/acr.2018.075. eCollection 2019 Apr-Jun.
Plasma cell cheilitis (PCC) is an inflammatory disorder of unknown etiology that affects the lip. It is characterized histologically by a dense infiltrate of plasma cells with a variety of clinical features. The response to different therapeutic modalities is controversial, especially regarding the effectiveness of corticosteroids. We present a case of a 56-year-old Caucasian man with a painful ulcerated and crusted area in the lower lip, resembling a squamous cell carcinoma or actinic cheilitis. Topical corticosteroid was used for one week, which resulted in partial regression and motivated a biopsy. The histological examination provided the diagnosis of PCC. The patient has been disease-free for six months. We also provide a discussion on the criteria of differential diagnosis and management of this rare condition.
浆细胞性唇炎（PCC）是一种病因不明的唇部炎症性疾病。其组织学特征为浆细胞密集浸润，并具有多种临床特征。对不同治疗方式的反应存在争议，尤其是关于皮质类固醇的有效性。我们报告一例56岁的白种男性病例，其下唇有一处疼痛的溃疡结痂区域，类似鳞状细胞癌或光化性唇炎。外用皮质类固醇治疗一周后，病情部分缓解，这促使进行活检。组织学检查确诊为浆细胞性唇炎。该患者已无病六个月。我们还对这种罕见疾病的鉴别诊断标准和治疗进行了讨论。
