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产后出血风险评估的现状与未来方向。

Current State and Future Direction of Postpartum Hemorrhage Risk Assessment.

机构信息

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee; and the Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Stanford, California.

出版信息

Obstet Gynecol. 2021 Dec 1;138(6):924-930. doi: 10.1097/AOG.0000000000004579.

DOI:10.1097/AOG.0000000000004579
PMID:34736271
Abstract

In the United States, postpartum hemorrhage is a leading preventable cause of maternal mortality and morbidity. To reduce morbidity from postpartum hemorrhage, risk assessment is an important starting point for informing decisions about risk management and hemorrhage prevention. Current perinatal care guidelines from the Joint Commission recommend that all patients undergo postpartum hemorrhage risk assessment at admission and after delivery. Three maternal health organizations-the California Maternal Quality Care Collaborative, AWHONN, and the American College of Obstetricians and Gynecologists' Safe Motherhood Initiative-have developed postpartum hemorrhage risk-assessment tools for clinical use. Based on the presence of risk factors, each organization categorizes patients as low-, medium-, or high-risk, and ties pretransfusion testing recommendations to these categorizations. However, the accuracy of these tools' risk categorizations has come under increasing scrutiny. Given their low positive predictive value, the value proposition of pretransfusion testing in all patients classified as medium- and high-risk is low. Further, 40% of all postpartum hemorrhage events occur in low-risk patients, emphasizing the need for early vigilance and treatment regardless of categorization. We recommend that maternal health organizations consider alternatives to category-based risk tools for evaluating postpartum hemorrhage risk before delivery.

摘要

在美国,产后出血是导致产妇死亡和发病的主要可预防原因。为了降低产后出血的发病率,风险评估是告知管理风险和预防出血决策的重要起点。联合委员会的现行围产期护理指南建议所有患者在入院时和分娩后进行产后出血风险评估。三个孕产妇健康组织——加利福尼亚孕产妇质量护理合作组织、美国妇产科医师学会和产妇安全倡议,已经开发了用于临床的产后出血风险评估工具。根据风险因素的存在,每个组织将患者分为低危、中危或高危,并将输血前检测建议与这些分类联系起来。然而,这些工具的风险分类准确性受到越来越多的关注。鉴于其低阳性预测值,对所有中高危分类患者进行输血前检测的价值主张较低。此外,40%的所有产后出血事件发生在低危患者中,这强调了无论分类如何,都需要早期警惕和治疗。我们建议孕产妇健康组织在分娩前考虑替代基于分类的风险工具来评估产后出血风险。

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