Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Department of Family Medicine and Community Health, Duke University, Durham, North Carolina, USA.
Hum Vaccin Immunother. 2021 Dec 2;17(12):5390-5396. doi: 10.1080/21645515.2021.1989919. Epub 2021 Nov 4.
Currently in the United States, Human Papillomavirus (HPV) vaccination coverage among eligible individuals is lower compared to coverage goals of 80% set by the HealthyPeople 2030 initiative. In this study, we used the National Health and Nutrition Examination Survey (NHANES) 2015-2016 and 2017-2018 datasets to determine the association between HPV vaccine initiation among individuals of ages 9 to 26 years and their patterns of healthcare access and utilization. In particular, we examined the following healthcare characteristics: 1) having a routine place of healthcare, 2) having health insurance coverage, 3) frequency of healthcare visits per year, and 4) type of routine place of healthcare (outpatient primary care vs. ED, etc.). We fit independent multivariable logistic regression models for each NHANES dataset and controlled for sociodemographic characteristics and interactions with healthcare access and utilization characteristics. Our findings suggest that HPV vaccine initiation is positively associated with having a routine place of healthcare (2015-2016: aOR 1.92, 95% CI 1.25-2.95; 2017-2018: aOR 1.99, 95% CI 1.07-3.68). Relatedly, HPV vaccine initiation is negatively associated with never having received healthcare in the past year (2015-2016: aOR 0.61, 95% CI 0.41-0.90; 2017-2018: aOR 0.45, 95% CI 0.27-0.75). The results of this study suggest that interventions to promote HPV vaccination should include strategies that promote access to and utilization of routine health care services. Our findings are particularly salient in light of the drop in HPV vaccine initiation and healthcare access and utilization among adolescents during the COVID-19 pandemic.
目前,美国符合条件的个人接种人乳头瘤病毒(HPV)疫苗的覆盖率低于“健康人 2030”倡议设定的 80%目标。在这项研究中,我们使用了 2015-2016 年和 2017-2018 年全国健康和营养检查调查(NHANES)数据集,以确定 9 至 26 岁个体接种 HPV 疫苗与他们获得和利用医疗保健服务模式之间的关联。具体而言,我们检查了以下医疗保健特征:1)有常规医疗场所,2)有医疗保险覆盖,3)每年接受医疗保健的次数,以及 4)常规医疗场所的类型(门诊初级保健与 ED 等)。我们为每个 NHANES 数据集拟合了独立的多变量逻辑回归模型,并控制了社会人口统计学特征以及与医疗保健获得和利用特征的相互作用。我们的研究结果表明,HPV 疫苗接种与有常规医疗场所(2015-2016 年:aOR1.92,95%CI1.25-2.95;2017-2018 年:aOR1.99,95%CI1.07-3.68)呈正相关。相关地,HPV 疫苗接种与过去一年从未接受过医疗保健呈负相关(2015-2016 年:aOR0.61,95%CI0.41-0.90;2017-2018 年:aOR0.45,95%CI0.27-0.75)。本研究结果表明,促进 HPV 疫苗接种的干预措施应包括促进获得和利用常规医疗保健服务的策略。考虑到 COVID-19 大流行期间青少年 HPV 疫苗接种和医疗保健获得和利用的下降,我们的研究结果尤为重要。