Caldwell Alexandria C, Madden Christi A, Thompson David M, Garbe M Connor, Roberts James R, Jacobson Robert M, Darden Paul M
Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Department of Biostatistics and Epidemiology, Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Hum Vaccin Immunother. 2021 Apr 3;17(4):1059-1067. doi: 10.1080/21645515.2020.1817713. Epub 2020 Oct 19.
This study explored the association between provider recommendation and adolescent vaccine coverage. We analyzed data from the 2008 to 2018 National Immunization Survey-Teen including coverage with one dose of quadrivalent meningococcal conjugate vaccine (MenACWY), Tetanus-diphtheria-acellular pertussis vaccine (Tdap), and one and three doses of Human papillomavirus (HPV) vaccine. We compared vaccine coverage between those who recalled a provider recommendation and those who did not. Among those who received a provider recommendation for MenACWY, coverage trended from 67.8% (2008) to 88.1% (2013), contrasted to those who did not, trending from 30.9% to 73.1%. Among those with a provider recommendation for Tdap, coverage trended from 47.6% to 89.7%, contrasted to those who did not, trending from 35.6% to 82.2%. Among females with a provider recommendation for HPV vaccine, receipt of initial dose of HPV vaccine trended from 57.5% (2008) to 74.3% (2018), contrasted to those who did not, trending from 18.1% to 49.8%, and among males, trended from 17.2% (2010) to 75.1% (2018) for those with a provider recommendation, compared to 0.5% to 44.7% for those without. In 2013, coverage difference by provider recommendation was 26.0% among females for one dose of HPV vaccine and 21.9% for three doses, and among males was 44.8% and 20.8%, respectively, while it was lower at 15% for MenACWY and 7.6% for Tdap. For each vaccine, coverage was higher with a provider recommendation; the largest difference was noted for HPV vaccine. This finding verifies for providers the importance of their recommendation, especially for the HPV vaccine.
本研究探讨了医疗服务提供者的建议与青少年疫苗接种覆盖率之间的关联。我们分析了2008年至2018年全国青少年免疫调查的数据，包括一剂四价脑膜炎球菌结合疫苗（MenACWY）、破伤风-白喉-无细胞百日咳疫苗（Tdap）以及一剂和三剂人乳头瘤病毒（HPV）疫苗的接种覆盖率。我们比较了回忆起医疗服务提供者建议的人群与未回忆起的人群之间的疫苗接种覆盖率。在那些收到医疗服务提供者关于MenACWY疫苗接种建议的人群中，接种覆盖率从2008年的67.8%上升至2013年的88.1%，而未收到建议的人群则从30.9%上升至73.1%。在那些收到医疗服务提供者关于Tdap疫苗接种建议的人群中，接种覆盖率从47.6%上升至89.7%，未收到建议的人群则从35.6%上升至82.2%。在收到医疗服务提供者关于HPV疫苗接种建议的女性中，HPV疫苗首剂接种率从2008年的57.5%上升至2018年的74.3%，未收到建议的女性则从18.1%上升至49.8%；在男性中，收到建议的人群从2010年的17.2%上升至2018年的75.1%，未收到建议的人群则从0.5%上升至44.7%。2013年，对于一剂HPV疫苗，女性中因医疗服务提供者建议导致的接种覆盖率差异为26.0%，三剂为21.9%；男性中分别为44.8%和20.8%，而MenACWY为15%，Tdap为7.6%。对于每种疫苗，有医疗服务提供者建议时的接种覆盖率更高；HPV疫苗的差异最为显著。这一发现向医疗服务提供者证实了他们建议的重要性，尤其是对于HPV疫苗。
