Department of Anesthesiology, the First Affiliated Hospital of Wannan Medical College, No. 2, Zheshan West Road, Jinghu District, Wuhu City, Anhui Province, China.
Department of Anesthesiology, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu Province, China.
BMC Anesthesiol. 2021 Nov 4;21(1):268. doi: 10.1186/s12871-021-01485-5.
The anatomical dimensions of the lumbar dural sac determine the sensory block level of spinal anesthesia; however, whether they show the same predictive value during continuous epidural anesthesia (CEA) remains undetermined. We designed the present study to verify the efficacy of the anatomical dimensions of the lumbar dural sac in predicting the sensory block level during labor analgesia.
A total of 122 parturients with singleton pregnancies requesting labor analgesia were included in this study. The lumbar dural sac diameter (DSD), lumbar dural sac length (DSL), lumbar dural sac surface area (DSA), and lumbar dural sac volume (DSV) were measured with an ultrasound color Doppler diagnostic apparatus. CEA was performed at the L2-L3 interspace. After epidural cannulation, an electronic infusion pump containing 0.08% ropivacaine and sufentanil 0.4 μg/ml was connected. The sensory block level was determined with alcohol-soaked cotton, a cotton swab, and a pinprick. The analgesic efficacy of CEA was determined with a visual analog scale (VAS). The parturients were divided into two groups, "ideal analgesia" and "nonideal analgesia," and the groups were compared by t test. Pearson's correlation was performed to evaluate the association between the anatomical dimensions of the lumbar dural sac and sensory block level. Multiple linear regression analysis was used to create a model for predicting the sensory block level.
In the ideal analgesia group, the height, DSL, DSA, DSV and DSD were significantly smaller, and the body mass index (BMI) was significantly larger (P < 0.05). In addition, the DSL demonstrated the strongest correlation with the peak level of pain block (r = - 0.816, P < 0.0001; Fig. 2A), temperature block (r = - 0.874, P < 0.0001; Fig. 3A) and tactile block (r = - 0.727, P < 0.0001; Fig. 4A). Finally, the multiple linear regression analysis revealed that DSL and BMI contributed to predicting the peak sensory block level.
In conclusion, our study shows that the sensory block level of CEA is higher when the DSL, DSA, DSV and DSD of puerperae are lower. DSL and BMI can be treated as predictors of the peak sensory block level in CEA during labor analgesia.
腰椎硬脊膜的解剖学尺寸决定了脊髓麻醉的感觉阻滞水平;然而,在连续硬膜外麻醉(CEA)中它们是否具有相同的预测价值仍不确定。我们设计了本研究,以验证腰椎硬脊膜解剖学尺寸在预测分娩镇痛时感觉阻滞水平的功效。
本研究共纳入 122 例要求分娩镇痛的单胎妊娠产妇。使用超声彩色多普勒诊断仪测量腰椎硬脊膜直径(DSD)、腰椎硬脊膜长度(DSL)、腰椎硬脊膜表面积(DSA)和腰椎硬脊膜体积(DSV)。在 L2-L3 间隙行 CEA。硬膜外导管置入后,连接含有 0.08%罗哌卡因和 0.4μg/ml舒芬太尼的电子输注泵。用酒精浸湿的棉花、棉签和针刺来确定感觉阻滞水平。用视觉模拟评分(VAS)来确定 CEA 的镇痛效果。将产妇分为“理想镇痛”和“非理想镇痛”两组,用 t 检验进行组间比较。Pearson 相关分析用于评估腰椎硬脊膜解剖学尺寸与感觉阻滞水平之间的关系。用多元线性回归分析创建预测感觉阻滞水平的模型。
在理想镇痛组中,身高、DSL、DSA、DSV 和 DSD 明显较小,体重指数(BMI)明显较大(P<0.05)。此外,DSL 与疼痛阻滞峰值水平相关性最强(r=-0.816,P<0.0001;图 2A)、温度阻滞(r=-0.874,P<0.0001;图 3A)和触觉阻滞(r=-0.727,P<0.0001;图 4A)。最后,多元线性回归分析显示,DSL 和 BMI 有助于预测感觉阻滞的峰值水平。
总之,我们的研究表明,产妇的 DSL、DSA、DSV 和 DSD 越低,CEA 的感觉阻滞水平越高。DSL 和 BMI 可作为 CEA 分娩镇痛时感觉阻滞峰值水平的预测指标。