与获得性补体缺乏相关的淋球菌极度易感性，继发于低补体血症性荨麻疹性血管炎和系统性红斑狼疮。
Extreme gonococcal susceptibility associated with acquired complement deficiency secondary to hypocomplementemic urticarial vasculitis and systemic lupus erythematosus.
机构信息
Department of Internal Medicine, Groupe Hospitalier Sud Ile de France, 77000, Melun, France.
Department of Infectious Diseases, Nord Franche-Comté Hospital, 90400, Trévenans, France.
出版信息
J Infect Chemother. 2022 Feb;28(2):308-310. doi: 10.1016/j.jiac.2021.10.020. Epub 2021 Nov 1.
Gonococcal infection is rarely associated with septic shock. We describe a recurrent case of septic shock related to disseminated gonococcemia in a patient with systemic lupus erythematosus and hypocomplementemic urticarial vasculitis, and discuss the implication of profound acquired complement deficiency secondary to these auto-immune diseases. This case raises the question of systematic antibioprophylaxis in patients with acquired complement deficiency.
淋病感染很少与感染性休克相关。我们描述了一例系统性红斑狼疮和低补体血症性荨麻疹性血管炎患者中反复发作的与播散性淋球菌血症相关的感染性休克病例，并讨论了这些自身免疫性疾病导致的严重获得性补体缺陷的影响。该病例提出了在获得性补体缺陷患者中进行系统抗生素预防的问题。
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