Department of Obstetrics and Gynecology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan.
Department of Nursing, Nagoya University Graduate School of Medicine, Nagoya, Japan.
J Int Med Res. 2021 Nov;49(11):3000605211054706. doi: 10.1177/03000605211054706.
The aim of this study was to examine the risk factors for antepartum hemorrhage (APH) in women with placenta previa.
In this retrospective cohort study, we analyzed the medical records of 233 women with singleton pregnancies presenting with placenta previa whose deliveries were performed at our hospital between January 2009 and July 2018.
Of the 233 women included in this study, 130 (55.8%) had APH. In the APH group, the gestational age and neonatal birth weight were significantly lower compared with the no hemorrhage group. Maternal age <30 years and multiparity were identified as significant risk factors for APH in both the univariate and multivariate analyses. Focusing on the previous route of delivery in multiparous women, the risk of APH was significantly higher in multiparous women who had experienced at least one vaginal delivery compared with nulliparous women (adjusted odds ratio (OR): 3.42 [95% confidence interval: 1.83-6.38]).
We showed that women with placenta previa who were under 30 years old and who had a history of vaginal delivery may be at significant risk of experiencing APH.
本研究旨在探讨前置胎盘孕妇发生产前出血(APH)的危险因素。
本回顾性队列研究分析了 2009 年 1 月至 2018 年 7 月在我院分娩的 233 例前置胎盘单胎妊娠妇女的病历。
本研究共纳入 233 例妇女,其中 130 例(55.8%)发生 APH。与无出血组相比,APH 组的胎龄和新生儿出生体重显著降低。在单因素和多因素分析中,年龄<30 岁和多产均被确定为 APH 的显著危险因素。在多产妇中,仅关注既往分娩方式时,与初产妇相比,至少有一次阴道分娩史的多产妇发生 APH 的风险显著增加(调整后的优势比(OR):3.42 [95%置信区间:1.83-6.38])。
我们表明,年龄<30 岁且有阴道分娩史的前置胎盘孕妇可能面临发生 APH 的显著风险。