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剖宫产术后子宫瘢痕与妊娠早期胎盘位置的前瞻性纵向研究。

Caesarean Section Scar and Placental Location at the First Trimester of Pregnancy-A Prospective Longitudinal Study.

机构信息

Department of Obstetrics and Gynaecology, Medicine Academy, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.

Department of Sports Medicine, Lithuanian University of Health Sciences, Tilzes Street' 18, 47181 Kaunas, Lithuania.

出版信息

Medicina (Kaunas). 2024 Apr 26;60(5):719. doi: 10.3390/medicina60050719.

DOI:10.3390/medicina60050719
PMID:38792902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11123301/
Abstract

: This study aims to report the location of the placenta in the first trimester of pregnancy in groups of women according to the number of previous caesarean deliveries and the visibility of the caesarean scar niche. : The prospective observational research included adult women aged 18 to 41 years during pregnancy after one or more previous caesarean sections (CSs). Transvaginal (TVS) and transabdominal sonography (TAS) was used to examine the uterine scar and placental location during 11-14 weeks. The CS scar niche ("defect") was bordered in the sagittal plane as a notch at the previous CS scar's site with a depth of 2.0 mm or more. A comparative analysis of the placental location (high or low and anterior or posterior) was performed between groups of women according to the CS number and the CS scar niche. : A total of 122 participants were enrolled during the first-trimester screening. The CS scar defect ("niche") was visible in 40.2% of cases. In cases after one previous CS, the placenta was low in the uterine cavity (anterior or posterior) at 77.4%, and after two or more CSs, it was at 67.9%. Comparing the two groups according to the CS scar niche, the placenta was low in 75.5% of cases in the participant group with a CS scar niche and in 75% of cases without a CS scar niche ( = 0.949). : The number of previous caesarean deliveries has no effect on the incidence rate of low-lying placentas in the first trimester. Moreover, the presence of the CS scar niche is not associated with anterior low-lying placentas.

摘要

本研究旨在报告根据既往剖宫产次数和剖宫产瘢痕憩室(CS 瘢痕憩室)可见性分组的孕妇在妊娠早期胎盘的位置。前瞻性观察性研究纳入了既往有一次或多次剖宫产的 18 至 41 岁成年孕妇。在 11-14 周时,采用经阴道超声(TVS)和经腹超声(TAS)检查子宫瘢痕和胎盘位置。CS 瘢痕憩室(“缺陷”)在矢状面以先前 CS 瘢痕部位的切迹边界,深度≥2.0mm。根据 CS 数量和 CS 瘢痕憩室,对不同 CS 数量和 CS 瘢痕憩室组的胎盘位置(高低和前后)进行了比较分析。在早孕期筛查期间,共有 122 名参与者入组。40.2%的病例可见 CS 瘢痕缺陷(“憩室”)。在既往有一次剖宫产的病例中,胎盘在子宫腔内位置较低(前后)的比例为 77.4%,在有两次或更多剖宫产的病例中,胎盘位置较低的比例为 67.9%。根据 CS 瘢痕憩室将两组进行比较,在有 CS 瘢痕憩室的参与者组中,胎盘位置较低的比例为 75.5%,在没有 CS 瘢痕憩室的参与者组中,胎盘位置较低的比例为 75%( = 0.949)。既往剖宫产次数对早孕期低置胎盘的发生率没有影响。此外,CS 瘢痕憩室的存在与前壁低置胎盘无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc0/11123301/8dcc54b1402a/medicina-60-00719-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc0/11123301/a165931de8b3/medicina-60-00719-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc0/11123301/8dcc54b1402a/medicina-60-00719-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc0/11123301/a165931de8b3/medicina-60-00719-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecc0/11123301/8dcc54b1402a/medicina-60-00719-g002.jpg

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本文引用的文献

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Pregnancy prediction via ultrasound-detected endometrial blood for hormone replacement therapy-frozen embryo transfer: a prospective observational study.经超声检测子宫内膜血流进行激素替代治疗-冷冻胚胎移植的妊娠预测:一项前瞻性观察研究。
Reprod Biol Endocrinol. 2023 Nov 24;21(1):112. doi: 10.1186/s12958-023-01164-9.
2
Aetiology, risk factors and preventive strategies for niche development: A review.生态位发展的病因、风险因素及预防策略:综述
Best Pract Res Clin Obstet Gynaecol. 2023 Aug;90:102363. doi: 10.1016/j.bpobgyn.2023.102363. Epub 2023 May 31.
3
ISUOG Practice Guidelines (updated): performance of 11-14-week ultrasound scan.
国际妇产科超声学会(ISUOG)实践指南(更新版):孕11 - 14周超声检查的实施
Ultrasound Obstet Gynecol. 2023 Jan;61(1):127-143. doi: 10.1002/uog.26106.
4
The link between intrauterine adhesions and impaired reproductive performance: a systematic review of the literature.宫腔粘连与生殖性能受损的关系:文献系统综述。
BMC Pregnancy Childbirth. 2022 Nov 14;22(1):837. doi: 10.1186/s12884-022-05164-2.
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Macrophage polarisation in caesarean scar diverticulum.剖宫产瘢痕憩室中的巨噬细胞极化
J Clin Pathol. 2023 Jun;76(6):379-383. doi: 10.1136/jclinpath-2021-207926. Epub 2022 Jan 3.
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Evaluation of the risk factors for antepartum hemorrhage in cases of placenta previa: a retrospective cohort study.前置胎盘性产前出血风险因素评估:一项回顾性队列研究。
J Int Med Res. 2021 Nov;49(11):3000605211054706. doi: 10.1177/03000605211054706.
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Transvaginal Sonographic Evaluation of Cesarean Section Scar Niche in Pregnancy: A Prospective Longitudinal Study.经阴道超声评估妊娠剖宫产术后子宫瘢痕憩室:一项前瞻性纵向研究。
Medicina (Kaunas). 2021 Oct 12;57(10):1091. doi: 10.3390/medicina57101091.
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Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age.高龄孕产妇所致高危妊娠的临床结局
J Womens Health (Larchmt). 2021 Feb;30(2):160-167. doi: 10.1089/jwh.2020.8860. Epub 2020 Nov 13.
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Rethinking Prenatal Screening for Anomalies of Placental and Umbilical Cord Implantation.重新思考胎盘和脐带植入异常的产前筛查。
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