Yang Jie, Ye Shaoxin, Xuan Bihua, Liu Zhengping, Fan Dazhi
Department of Obstetrics, The Affiliated Foshan Women and Children Hospital, Guangdong Medical University, Foshan, Guangdong, China.
Foshan Fetal Medicine Research Institute, The Affiliated Foshan Women and Children Hospital, Guangdong Medical University, Foshan, Guangdong, China.
PeerJ. 2025 Feb 25;13:e19091. doi: 10.7717/peerj.19091. eCollection 2025.
Antepartum hemorrhage (APH) is associated with perinatal mortality and maternal morbidity. Previous studies have reported that obesity in pregnancy adversely influences both fetal and neonatal outcomes. This study aimed to investigate gestational overweight and the risk of APH in pregnant women with complete placenta previa (CPP).
This was a retrospective cohort study of pregnant women with CPP delivery at our hospital from 2013 to 2015. Outcomes were stratified according to APH and non-APH.
Of 193 pregnancies with CPP, 40.4% (78) were diagnosed with APH. Maternal weight and BMI at delivery were significantly decreased in women with APH (61.15 ± 8.73 . 65.22 ± 7.80, 24.47 ± 3.12 . 26.21 ± 2.85; = 0.001, = 0.001; respectively), and the prevalence of overweight at delivery was higher in the non-APH group compared to those in the APH group (54.9% (62) . 39.7% (27); OR 2.18; 95%CI [1.16-4.11]). After adjusting for gestation week and other potential confounding factors, maternal weight and BMI were associated with the APH (OR 0.95, 95%CI [0.91-0.99]; 0.85, 95%CI [0.75-0.97], respectively).
Appropriate weight gain during pregnancy may decrease the risk of antepartum hemorrhage in pregnant women with complete placenta previa.
产前出血（APH）与围产期死亡率和孕产妇发病率相关。既往研究报道，孕期肥胖会对胎儿和新生儿结局产生不利影响。本研究旨在调查完全性前置胎盘（CPP）孕妇的孕期超重情况及产前出血风险。
这是一项对2013年至2015年在我院分娩的CPP孕妇进行的回顾性队列研究。结局根据产前出血和未发生产前出血进行分层。
在193例CPP妊娠中，40.4%（78例）被诊断为产前出血。产前出血的女性分娩时的体重和BMI显著降低（分别为61.15±8.73、65.22±7.80、24.47±3.12、26.21±2.85；P = 0.001，P = 0.001），未发生产前出血组分娩时超重的患病率高于产前出血组（54.9%（62例）对39.7%（27例）；OR 2.18；95%CI[1.16 - 4.11]）。在调整孕周和其他潜在混杂因素后，孕妇体重和BMI与产前出血相关（OR分别为0.95，95%CI[0.91 - 0.99]；0.85，95%CI[0.75 - 0.97]）。
孕期适当增加体重可能会降低完全性前置胎盘孕妇产前出血的风险。
