从 mRNA 感应到疫苗。

From mRNA sensing to vaccines.

出版信息

Immunity. 2021 Dec 14;54(12):2676-2680. doi: 10.1016/j.immuni.2021.10.018. Epub 2021 Nov 4.

DOI:10.1016/j.immuni.2021.10.018

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8567413/

Abstract

The 2005 Immunity paper by Karikó et al. has been hailed as a cornerstone insight that directly led to the design and delivery of the mRNA vaccines against COVID-19. We asked experts in pathogen sensing, vaccine development, and public health to provide their perspective on the study and its implications.

摘要

由 Karikó 等人撰写的 2005 年免疫学期刊论文被誉为一项重要的见解，它直接促成了针对 COVID-19 的 mRNA 疫苗的设计和交付。我们请病原体感应、疫苗开发和公共卫生方面的专家提供他们对这项研究及其影响的看法。