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近端胃癌根治术后双瓣技术的功能获益。

Functional benefits of the double flap technique after proximal gastrectomy for gastric cancer.

机构信息

Department of Gastrointestinal Tract Surgery, Fukushima Medical University, Hikarigaoka, Fukushima-shi, Fukushima, 960-1295, Japan.

出版信息

BMC Surg. 2021 Nov 5;21(1):392. doi: 10.1186/s12893-021-01390-1.

Abstract

BACKGROUND

Proximal gastrectomy is a widely performed procedure that has become more common with an increasing number of proximal gastric cancer cases. Several types of reconstructive procedures after proximal gastrectomy have been developed, and it remains controversial which procedure is the most advantageous with regard to the preservation of postoperative gastric stump function and nutritional status. In the present study, we retrospectively analyzed reconstructive procedures in a consecutive case series for proximal gastrectomy, primarily focusing on postoperative body weight maintenance, nutritional status, and gastric remnant functional preservation.

METHODS

We enrolled 69 patients who had undergone proximal gastrectomy for gastric cancer in our institute between 2005 and 2020. Short-term complications, preservation of gastric remnant functions, nutritional status, and post-operative weight changes were compared.

RESULTS

After proximal gastrectomy, the numbers of patients who underwent direct esophago-gastrostomy, jejunal interposition, double tract reconstruction, and the double flap technique were 9, 10, 14, and 36, respectively. The patients in whom the double flap technique was performed suffered no reflux esophagitis after surgery. Prevalence of gastric residual at 12 months after surgery was lowest in the double flap technique group. Moreover, the double flap technique group had a better tendency regarding post-operative changes of serum albumin ratios. Furthermore, the post-operative body weight change ratio of the double flap technique group was smallest among all groups and was significantly better than that of the double tract group.

CONCLUSIONS

The double flap technique after proximal gastrectomy was considered the most effective technique for reconstruction which leads to better bodyweight maintenance, and results in less reflux esophagitis.

摘要

背景

近端胃切除术是一种广泛开展的手术,随着近端胃癌病例的增多,其应用也越来越普遍。已经开发出几种类型的近端胃切除术后重建术,关于哪种手术在保留术后胃残端功能和营养状况方面最有利,仍存在争议。在本研究中,我们对连续的近端胃切除术病例系列进行了回顾性分析,主要关注术后体重维持、营养状况和胃残端功能保留。

方法

我们纳入了 2005 年至 2020 年在我院接受近端胃切除术治疗胃癌的 69 例患者。比较了短期并发症、胃残端功能保留、营养状况和术后体重变化。

结果

近端胃切除术后,行直接食管胃吻合术、空肠间置术、双管重建术和双瓣技术的患者分别为 9、10、14 和 36 例。行双瓣技术的患者术后无反流性食管炎。术后 12 个月胃残存量最低的是双瓣技术组。此外,双瓣技术组术后血清白蛋白比值变化的趋势更好。此外,双瓣技术组术后体重变化率在所有组中最小,明显优于双管组。

结论

近端胃切除术后行双瓣技术被认为是最有效的重建技术,可更好地维持体重,减少反流性食管炎的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec68/8569978/71a3f3708f0c/12893_2021_1390_Fig1_HTML.jpg

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