Department of Radilogy, Seirei Hamamatsu General Hospital, 2-12, Sumiyoshi, Naka ward, Hamamatsu, 430-8558, Shizuoka, Japan.
School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, 470-1192 Toyoake, Japan.
Cancer Radiother. 2022 Jun;26(4):547-556. doi: 10.1016/j.canrad.2021.07.038. Epub 2021 Nov 2.
Surface-guided radiotherapy is useful for the pre-positioning and monitoring of radiotherapy. The purpose of this study was to investigate the impact of surface guidance on the repeatability of patient localization and to estimate the specific point at which high positional errors occur.
Ten patients without the VOXELAN system (non-VXLN group) and 10 patients with the VOXELAN as the pre-positioning procedure (VXLN group) were included in this analysis. Twelve regions of interest (ROI) were defined in all the patients to verify any misalignment during radiotherapy. Thirteen ROIs were defined on the isocenter.
Compared with the non-VXLN group, the translational positional errors of the VXLN group were the same for all the ROIs. The mean translational positional errors of the VXLN group in the longitudinal direction were approximately 0.1mm, and the standard deviation was the largest among the three directions in all the ROIs. The magnitude of the standard deviation in the non-VXLN group varied independently of the ROI and direction. The standard deviations of the VXLN group in the longitudinal direction were large in all the ROIs, while the standard deviations in the vertical and lateral directions were small.
Pre-positioning with a surface guidance system reduced the body twist and rotation, which could not be corrected by image-guided radiotherapy alone. Since the VOXELAN can detect positioning errors quickly and without additional radiation exposure to the patient, it can be used as a tool for pre-positioning in radiotherapy.
表面引导放疗有助于放疗的定位和监测。本研究旨在探讨表面引导对患者定位重复性的影响,并估计出现高定位误差的具体位置。
本分析纳入 10 名未使用 VOXELAN 系统(非 VXLN 组)的患者和 10 名使用 VOXELAN 进行预定位的患者(VXLN 组)。所有患者均定义了 12 个感兴趣区域(ROI),以验证放疗过程中的任何错位。在等中心点定义了 13 个 ROI。
与非 VXLN 组相比,VXLN 组所有 ROI 的平移定位误差相同。VXLN 组在纵向方向上的平均平移定位误差约为 0.1mm,且在所有 ROI 的三个方向中,标准差最大。非 VXLN 组的标准差大小独立于 ROI 和方向变化。VXLN 组在所有 ROI 的纵向方向上的标准差较大,而在垂直和水平方向上的标准差较小。
使用表面引导系统进行预定位可减少因图像引导放疗无法单独纠正的身体扭曲和旋转。由于 VOXELAN 可以快速检测定位误差,且不会对患者额外暴露于辐射,因此可作为放疗中预定位的工具。