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无法治愈癌症患者的营养状况与原发肿瘤部位。

Nutritional status and primary tumour site in incurable cancer.

机构信息

Palliative Care Unit, José Alencar Gomes da Silva National Cancer Institute (INCA), Rio de Janeiro, Brazil

Palliative Care Unit, José Alencar Gomes da Silva National Cancer Institute (INCA), Rio de Janeiro, Brazil.

出版信息

BMJ Support Palliat Care. 2024 Aug 19;14(3):308-316. doi: 10.1136/bmjspcare-2021-003321.

DOI:10.1136/bmjspcare-2021-003321
PMID:34740940
Abstract

OBJECTIVES

We aimed (1) to assess the nutritional status (NS) using different methods, according to the primary tumour site and (2) to evaluate the performance of these methods in patients with incurable cancer from a reference centre in Brazil.

METHODS

Cross-sectional analysis of data from patients admitted to the palliative care unit of a reference cancer centre in Brazil, between July 2016 and March 2020. The primary tumour site was the independent variable and the NS using different methods were the dependent variables. Logistic regressions were performed.

RESULTS

A total of 2,144 patients were included in the study. The most common primary tumour site was the upper gastrointestinal (GI) tract (18.0%), followed by gynaecological (17.6%) and head and neck (HN) (13.5%). Our results showed that patients with tumours of the upper GI tract followed by HN presented significantly higher risk of worse NS. breast tumours, bone and connective tissues and melanoma presented inverse association. .

CONCLUSIONS

atients with incurable cancer present high prevalence of NS impairment, depending on the tumour site, shown to be elevated in patients with tumour in the upper GI tract.

摘要

目的

根据原发肿瘤部位,(1)使用不同方法评估营养状况(NS),(2)评估这些方法在巴西参考中心不可治愈癌症患者中的表现。

方法

对 2016 年 7 月至 2020 年 3 月期间在巴西一家癌症参考中心姑息治疗病房住院的患者进行横断面数据分析。原发肿瘤部位为自变量,使用不同方法的 NS 为因变量。进行逻辑回归分析。

结果

共纳入 2144 例患者。最常见的原发肿瘤部位是上消化道(GI)(18.0%),其次是妇科(17.6%)和头颈部(HN)(13.5%)。我们的结果表明,上消化道肿瘤继头颈部肿瘤的患者,NS 恶化的风险显著更高。而乳腺癌、骨和结缔组织以及黑色素瘤则呈现出相反的关联。

结论

不可治愈癌症患者的 NS 损伤患病率较高,具体取决于肿瘤部位,上消化道肿瘤患者的 NS 损伤患病率更高。

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