1 National Cancer Institute José Alencar Gomes da Silva (INCA), Rio de Janeiro, RJ, Brazil.
2 Department of Nutrition and Dietetics, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Nutr Clin Pract. 2017 Oct;32(5):675-681. doi: 10.1177/0884533617725071. Epub 2017 Aug 29.
The purpose of this study was to evaluate the prognostic significance of the Patient-Generated Subjective Global Assessment (PG-SGA) in patients receiving palliative care for advanced cancer.
The PG-SGA was used to assess nutrition status of 120 patients admitted to the Palliative Care Unit at the National Cancer Institute in Brazil.
According to the PG-SGA, 94.2% (n = 113) of the patients were evaluated as malnourished. The PG-SGA evaluated that xerostomia was the only symptom associated with a short survival (odds ratio [OR], 2.54; 95% confidence interval [CI], 1.2-5.38; P = .014). Survival was found to be significantly higher in well-nourished (PG-SGA A) than malnourished (PG-SGA B [ P = .021] or C [ P = .013]) patients. Total PG-SGA score (hazard ratio [HR], 1.06; 95% CI, 1.001-1.09; P = .045) and Karnofsky Performance Status of 20%-30% (HR, 15.4; 95% CI, 1.63-92.9; P = .001) and 40%-50% (HR, 10.0; 95% CI, 1.22-64.9; P = .031) were found to be independent prognostic survival factors.
The scored PG-SGA is an independent prognostic factor of survival and thus can be a useful tool for nutrition evaluation in palliative care.
本研究旨在评估患者自评主观整体评估（PG-SGA）在接受姑息治疗的晚期癌症患者中的预后意义。
使用 PG-SGA 评估了巴西国家癌症研究所姑息治疗病房的 120 名患者的营养状况。
根据 PG-SGA，94.2%（n=113）的患者被评估为营养不良。PG-SGA 评估发现口干是与生存期缩短唯一相关的症状（比值比[OR]，2.54；95%置信区间[CI]，1.2-5.38；P=0.014）。与营养不良（PG-SGA B[P=0.021]或 C[P=0.013]）患者相比，营养良好（PG-SGA A）患者的生存显著更高。总 PG-SGA 评分（风险比[HR]，1.06；95%CI，1.001-1.09；P=0.045）和 Karnofsky 表现状态 20%-30%（HR，15.4；95%CI，1.63-92.9；P=0.001）和 40%-50%（HR，10.0；95%CI，1.22-64.9；P=0.031）被发现是独立的预后生存因素。
评分 PG-SGA 是生存的独立预后因素，因此可以作为姑息治疗中营养评估的有用工具。
