Vetchaporn Sirikanlaya, Rangsri Wetchayan, Ittichaicharoen Jitjiroj, Rungsiyakull Pimduen
Division of Geriatric Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.
Intercountry Centre for Oral Health, Department of Health, Ministry of Public Health, Chiang Mai 50000, Thailand.
Int J Dent. 2021 Oct 29;2021:6814027. doi: 10.1155/2021/6814027. eCollection 2021.
There is limited documentation of using fluorescence images in oral potentially malignant disorders (OPMDs) and oral cancer screening through the field of teledentistry. This study aims to develop and evaluate the validity and reliability of the intraoral camera with the combination method of autofluorescence and LED white light used for OPMDs and oral cancer screening in teledentistry. The intraoral camera with fluorescent aids, which uses a combined method of both autofluorescence and LED white light, was developed before the device was evaluated for validity and reliability as a OPMDs screening tool for teledentistry. All lesions of thirty-four OPMD patients underwent biopsy for definitive diagnosis and were examined by an oral medicine specialist. Both images under autofluorescent and LED white light mode captured from the device were sent online and interpreted for the initial diagnosis and dysplastic features in addition to being compared to the direct clinical examination and histopathological findings. The combination method was also compared with autofluorescence method alone. The device provided good image quality, which was enough for initial diagnosis. Using the combination method, sensitivity, specificity, PPV, and NPV of the device via teledentistry were 87.5%, 84.6%, 63.6%, and 95.7%, respectively, which were higher than autofluorescence method alone in every parameter. The concordance of dysplastic lesion was 85.29% and 79.41% for category of lesion. The validity and reliability results of the combination method for the screening of dysplasia in OPMDs were higher than autofluorescent method alone. The intraoral camera with fluorescent aids for the OPMDs screening can be utilized for screening via teledentistry.
关于通过远程口腔医学领域，利用荧光图像进行口腔潜在恶性疾病（OPMDs）和口腔癌筛查的文献记载有限。本研究旨在开发并评估结合了自发荧光和LED白光的口腔内摄像头用于远程口腔医学中OPMDs和口腔癌筛查的有效性和可靠性。在将该带有荧光辅助装置的口腔内摄像头作为远程口腔医学中OPMDs筛查工具进行有效性和可靠性评估之前，就已开发出了这种采用自发荧光和LED白光组合方法的设备。34例OPMD患者的所有病变均接受活检以明确诊断，并由口腔医学专家进行检查。从该设备采集的自发荧光和LED白光模式下的图像均在线发送，并用于初步诊断和发育异常特征分析，此外还与直接临床检查和组织病理学结果进行比较。该组合方法还与单独的自发荧光方法进行了比较。该设备提供了良好的图像质量，足以用于初步诊断。通过远程口腔医学使用该组合方法时，该设备的灵敏度、特异性、阳性预测值和阴性预测值分别为87.5%、84.6%、63.6%和95.7%，在每个参数上均高于单独的自发荧光方法。发育异常病变类别的一致性在病变类别方面分别为85.29%和79.41%。用于OPMDs发育异常筛查的组合方法的有效性和可靠性结果高于单独的自发荧光方法。带有荧光辅助装置的用于OPMDs筛查的口腔内摄像头可用于通过远程口腔医学进行筛查。
