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基于空间光调制器的干涉仪用于评估眼睛的多色神经传递函数。

SLM-based interferometer for assessing the polychromatic neural transfer function of the eye.

作者信息

Suchkov Nikolai, Kurian Tobin, Schwarz Christina, Leube Alexander, Wahl Siegfried

机构信息

Institute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen 72076, Germany.

Carl Zeiss Vision International GmbH, Aalen 73430, Germany.

出版信息

Biomed Opt Express. 2021 Sep 7;12(10):6040-6054. doi: 10.1364/BOE.432744. eCollection 2021 Oct 1.

Abstract

A novel interferometric instrument for measuring neural transfer function (NTF) of the eye is presented. The device is based on a liquid-crystal-on-silicon spatial light modulator (SLM), which is used to create two laterally separated wavefronts in the pupil plane of the eye that interfere on the retina. The phase mask on the SLM, consisting of two diffraction gratings mixed in a checkerboard pattern and acting as a shearing interferometer, allows independent control of spatial frequency, orientation, and contrast of the fringes, as well as the field of view in a wide polychromatic spectrum. Coupled with a supercontinuum source, the system is able to produce achromatic fringes on the retina. The instrument was successfully tested in six normal subjects in four light conditions: polychromatic light and monochromatic blue, green and red light respectively (central wavelengths - 450, 550 and 650 nm). On average, the NTF in polychromatic light was approximately 20% higher than for green and red light, although not statistically significant due to high intersubject variability. Due to all-digital control of the interference fringes, the device is optically simple and virtually unsusceptible to vibrations, allowing its use in a non-laboratory environment. The study also contributes to color vision research, allowing to evaluate contrast sensitivity function without monochromatic or chromatic aberrations.

摘要

介绍了一种用于测量眼睛神经传递函数(NTF)的新型干涉仪。该设备基于硅基液晶空间光调制器(SLM),用于在眼睛的瞳孔平面中创建两个横向分离的波前,它们在视网膜上发生干涉。SLM上的相位掩模由以棋盘图案混合的两个衍射光栅组成,用作剪切干涉仪,可独立控制条纹的空间频率、方向和对比度,以及宽多色光谱中的视场。与超连续光源相结合,该系统能够在视网膜上产生消色差条纹。该仪器在六名正常受试者中分别在四种光照条件下成功进行了测试:多色光以及单色蓝光、绿光和红光(中心波长分别为450、550和650nm)。平均而言,多色光下的NTF比绿光和红光下的NTF高约20%,尽管由于个体间差异较大,差异无统计学意义。由于干涉条纹的全数字控制,该设备光学结构简单,几乎不受振动影响,可在非实验室环境中使用。该研究还为色觉研究做出了贡献,能够在没有单色或色差的情况下评估对比敏感度函数。

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