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乙状结肠腔内寄生性平滑肌瘤及其潜在发病机制

An Intraluminal Parasitic Leiomyoma of the Sigmoid Colon and Potential Pathogenetic Mechanisms.

作者信息

Marasioni Maria Dimitra, Tsarna Ermioni, Tsochrinis Alexios, Chavez Nestor, Georgopapadakos Nikolaos

机构信息

Department of Obstetrics and Gynecology, General Hospital of Nikaia "Agios Panteleimon", Piraeus, GRC.

出版信息

Cureus. 2021 Oct 3;13(10):e18451. doi: 10.7759/cureus.18451. eCollection 2021 Oct.

DOI:10.7759/cureus.18451
PMID:34745776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8561668/
Abstract

Uterine leiomyomas are the most common benign tumor of the female pelvis. Parasitic leiomyomas are an extremely rare entity of leiomyoma occurrence found at extrauterine sites. They are mostly diagnosed in patients with a history of gynecologic procedures and morcellators use during laparoscopic leiomyoma resection. Here we present an extraordinary case of an intraluminal leiomyoma of the sigmoid colon that was incidentally discovered during total abdominal hysterectomy and bilateral salpingo-oophorectomy, performed due to leiomyomatous uterus in a female patient with no history of previous gynecologic operations. Potential pathogenetic mechanisms that can explain the co-occurrence of leiomyomas in the uterus and the sigmoid colon are also reviewed and include genetic predisposition, the stem cell theory of leiomyomas formation, and lymphatic and vascular spread.

摘要

子宫平滑肌瘤是女性盆腔最常见的良性肿瘤。寄生性平滑肌瘤是一种极其罕见的平滑肌瘤发生类型,见于子宫外部位。它们大多在有妇科手术史且在腹腔镜平滑肌瘤切除术中使用粉碎器的患者中被诊断出来。在此,我们报告一例乙状结肠腔内平滑肌瘤的特殊病例,该病例是在一名无既往妇科手术史的女性患者因子宫平滑肌瘤行全腹子宫切除术及双侧输卵管卵巢切除术时偶然发现的。本文还回顾了可解释子宫和乙状结肠同时出现平滑肌瘤的潜在发病机制,包括遗传易感性、平滑肌瘤形成的干细胞理论以及淋巴和血管扩散。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c21/8561668/68bdf00c6358/cureus-0013-00000018451-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c21/8561668/8e1268c60eb6/cureus-0013-00000018451-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c21/8561668/68bdf00c6358/cureus-0013-00000018451-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c21/8561668/8e1268c60eb6/cureus-0013-00000018451-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c21/8561668/68bdf00c6358/cureus-0013-00000018451-i02.jpg

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Sigmoid Leiomyoma: An Uncommon Occurrence.乙状结肠平滑肌瘤:一种罕见病例。
Cureus. 2020 Apr 6;12(4):e7567. doi: 10.7759/cureus.7567.
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A rare case of paratesticular leiomyoma in a child.一例儿童睾丸旁平滑肌瘤的罕见病例。
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