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2
Cerebral venous sinus thrombosis after vestibular schwannoma surgery: a call for evidence-based management guidelines.前庭神经鞘瘤手术后的脑静脉窦血栓形成:呼吁制定基于证据的管理指南。
Neurosurg Focus. 2018 Jul;45(1):E4. doi: 10.3171/2018.4.FOCUS18112.
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Incidence and Risk Factors for Sigmoid Venous Thrombosis Following CPA Tumor Resection.CPA 肿瘤切除术后乙状窦血栓形成的发生率及危险因素。
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4
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J Neurosurg. 2017 Jan;126(1):8-16. doi: 10.3171/2015.11.JNS151881. Epub 2016 Feb 26.
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颅底手术后急性乙状窦受压:“放任自流”的方法是最佳选择吗?

Acute Sigmoid Sinus Compromise Following Skull Base Procedures: Is a "Laissez-Faire" Approach Best?

作者信息

Arnone Gregory D, Kunigelis Katherine E, Gurau Andrei, Coulter Ian, Thompson John, Youssef A Samy

机构信息

Department of Neurosurgery, University of Colorado, Aurora, Colorado, United States.

School of Medicine, University of Colorado, Aurora, Colorado, United States.

出版信息

J Neurol Surg B Skull Base. 2020 Oct 5;82(6):652-658. doi: 10.1055/s-0040-1715811. eCollection 2021 Dec.

DOI:10.1055/s-0040-1715811
PMID:34745833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8563264/
Abstract

Venous sinus compromise (VSC) of the sigmoid sinus can manifest as either venous sinus thrombosis, stenosis, or a combination of the two. It may occur following retro and presigmoid craniotomy, even in the absence of overt intraoperative sinus injury. Currently, the optimal management of VSC in the perioperative period is not well established. We report our incidence and management of VSC following skull base surgery around the sigmoid sinus.  A retrospective chart review of all patients undergoing presigmoid, retrosigmoid, or combined approach by the senior author from 2014 to 2019 was performed.  Charts were reviewed for patient demographics, surgical details, details of venous sinus compromise, and patient outcomes. Statistical analyses were performed using R 3.6.0 (R Project).  A 115 surgeries were found with a total of 13 cases of VSC (overall incidence of 11.3%). Nine cases exhibited thrombosis and four stenosis. There were no statistically significant differences between the groups with (group 1) or without (group 2) VSC. Operation on the side of the dominant sinus did not predispose to postoperative VSC. Five patients received antiplatelet medication in the perioperative period. There was no difference in outcomes in the group that did not receive antiplatelet medication versus those who did.  Acute iatrogenic sigmoid sinus compromise can be managed expectantly. We believe that the treatment for each instance of VSC must be individualized, considering the symptoms of the patient, rather than applying a universal algorithm.

摘要

乙状窦的静脉窦受压(VSC)可表现为静脉窦血栓形成、狭窄或两者兼而有之。它可能发生在乙状窦后和乙状窦前开颅术后,即使在术中没有明显的静脉窦损伤的情况下。目前,围手术期VSC的最佳管理方法尚未明确。我们报告了在乙状窦周围颅底手术后VSC的发生率及处理情况。

对2014年至2019年由资深作者进行乙状窦前、乙状窦后或联合入路手术的所有患者进行了回顾性病历审查。

审查病历以获取患者人口统计学信息、手术细节、静脉窦受压细节和患者预后情况。使用R 3.6.0(R项目)进行统计分析。

共发现115例手术,其中13例发生VSC(总发生率为11.3%)。9例表现为血栓形成,4例为狭窄。有VSC组(第1组)和无VSC组(第2组)之间无统计学显著差异。在优势窦一侧进行手术并不会增加术后VSC的风险。5例患者在围手术期接受了抗血小板药物治疗。未接受抗血小板药物治疗的组与接受治疗的组在预后方面没有差异。

急性医源性乙状窦受压可进行观察处理。我们认为,对于每一例VSC的治疗都必须个体化,要考虑患者的症状,而不是应用通用的算法。