Deckers Leme Mateus, Elias Gilio Alfredo
Nove de Julho University, Osasco, Brazil.
Hospital Universitário, São Paulo University, São Paulo, Brazil.
Vaccine X. 2021 Oct 19;9:100118. doi: 10.1016/j.jvacx.2021.100118. eCollection 2021 Dec.
Health workers are a risk population for many infectious diseases, which leads to a number of vaccines being routinely recommended for health care staff. Medical students are also prone to such hazards. This study accesses undergraduate medicine students' compliance to recommended health-staff vaccination, and their reasons for noncompliance.
An online questionnaire was sent to all undergraduates in a major public medical school in Brazil, asking about vaccination status to Hepatitis B, Measle-mumps-rubella, Varicella, Pertussis and Influenza, and reasons in case of noncompliance.
146 students answered the questionnaire, (response rate 14,6%). Overall vaccination status showed 74,7% of students with incomplete vaccination in some way, with an increase in vaccination status toward the end of the course. The highest noncompliance rates were Pertussis (49,3%), Varicella (47,3%) and Influenza (30,1%) vaccines. The vaccine with the lowest noncompliance rate was measles (9,6%). During the course, the greatest increases in adequate vaccination status were Hepatitis B, from 53,2% in first-years to 93,2% by the end sixth year (chi-sq 21, p < 0,0001), and Influenza, from 48,9% to 91,5% (chi-sq 22,5, p < 0,00009). Main reasons given not to vaccinate were vaccination hesitancy for influenza and varicella (respectively 61% and 46%), and lack of awareness of the need to vaccinate for pertussis (53%).
Overall vaccine coverage in medical students in Brazil is still far from optimal. There is a markedly high level of vaccine hesitancy and unawareness of need to vaccinate for some diseases, particularly pertussis and influenza.Clinical trial registry (Brazilian regulation boards): 24159119.3.0000.0065.
卫生工作者是许多传染病的高危人群，这导致多项疫苗被常规推荐给医护人员。医学生也容易面临此类风险。本研究调查了本科医学生对推荐的医护人员疫苗接种的依从性及其不依从的原因。
向巴西一所主要公立医学院的所有本科生发送了一份在线问卷，询问他们的乙肝、麻疹-腮腺炎-风疹、水痘、百日咳和流感疫苗接种状况，以及不接种的原因。
146名学生回答了问卷（回复率14.6%）。总体疫苗接种状况显示，74.7%的学生在某种程度上接种不完全，且在课程结束时接种状况有所改善。不依从率最高的是百日咳疫苗（49.3%）、水痘疫苗（47.3%）和流感疫苗（30.1%）。不依从率最低的疫苗是麻疹疫苗（9.6%）。在课程期间，充分接种状况改善最大的是乙肝疫苗，从一年级的53.2%增至六年级末的93.2%（卡方值21，p<0.0001），以及流感疫苗，从48.9%增至91.5%（卡方值22.5，p<0.00009）。不接种疫苗的主要原因是对流感和水痘疫苗接种犹豫不决（分别为61%和46%），以及对百日咳疫苗接种必要性缺乏认识（53%）。
巴西医学生的总体疫苗接种覆盖率仍远未达到最佳水平。对某些疾病，尤其是百日咳和流感，存在明显的疫苗接种犹豫和对接种必要性缺乏认识的情况。临床试验注册（巴西监管委员会）：24159119.3.0000.0065 。
