D'Orazio Beatrice, Bonventre Sebastiano, Cudia Bianca, Di Vita Gaetano, Geraci Girolamo
General Surgery Unit - Department of Surgical, Oncological and Stomatological Sciences, University of Palermo; Postgraduate Medical School in General Surgery, University of Palermo, Palermo.
General Surgery Unit - Department of Surgical, Oncological and Stomatological Sciences, University of Palermo.
Acta Biomed. 2021 Nov 4;92(S1):e2021112. doi: 10.23750/abm.v92iS1.11201.
Malignant gastrointestinal melanoma is usually a metastatic lesion. We report the case of a 79-year-old female asymptomatic patient. Colonoscopy revealed one plane 15 mm pigmented lesion in the caecum. Neither CT scan of the abdomen nor right hemicolectomy revealed no metastatic disease. Histopathological examination of the surgical specimen was indicative of malignant melanoma.A set of additional enquires such as laboratory and imaging tests did not point out any suspicious lesions in the skin, eye, leptomeninges or other sites. Therefore, we made the diagnosis of primary colonic melanoma.The diagnosis of this disease is still a challange and often demanding for a multidisciplinary approach, involving the surgeon, onclogist and even immunotherapy or radiotherapy.
恶性胃肠道黑色素瘤通常是转移性病变。我们报告一例79岁无症状女性患者的病例。结肠镜检查发现盲肠有一个15毫米的扁平色素沉着病变。腹部CT扫描和右半结肠切除术均未发现转移性疾病。手术标本的组织病理学检查提示为恶性黑色素瘤。一系列额外检查，如实验室和影像学检查，未发现皮肤、眼睛、软脑膜或其他部位有任何可疑病变。因此，我们诊断为原发性结肠黑色素瘤。这种疾病的诊断仍然是一项挑战，通常需要多学科方法，涉及外科医生、肿瘤学家，甚至免疫治疗或放射治疗。
