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本文引用的文献

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Malignant melanoma metastasis as a cause of small-bowel perforation.恶性黑色素瘤转移导致小肠穿孔。
Onkologie. 2009 Jun;32(6):356-8. doi: 10.1159/000215718. Epub 2009 May 19.
2
Melanoma of the small intestine.小肠黑色素瘤
Lancet Oncol. 2009 May;10(5):516-21. doi: 10.1016/S1470-2045(09)70036-1.
3
Small-bowel endoscopy is crucial for diagnosis of melanoma metastases to the small bowel: a case of metachronous small-bowel metastases and review of the literature.小肠内镜检查对于诊断黑色素瘤小肠转移至关重要:一例异时性小肠转移病例及文献复习
Melanoma Res. 2007 Oct;17(5):335-8. doi: 10.1097/CMR.0b013e3282c3a706.
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Metastatic melanoma causing jejunal intussusception.转移性黑色素瘤导致空肠套叠。
J Gastrointest Surg. 2007 Dec;11(12):1755-7. doi: 10.1007/s11605-007-0215-y. Epub 2007 Jul 10.
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Metastatic melanoma presenting as a perforated small bowel.以小肠穿孔形式表现的转移性黑色素瘤。
Turk J Gastroenterol. 2006 Sep;17(3):223-5.
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Metastatic malignant melanoma of the gastrointestinal tract.胃肠道转移性恶性黑色素瘤
Mayo Clin Proc. 2006 Apr;81(4):511-6. doi: 10.4065/81.4.511.
7
Perforation of metastatic melanoma to the small bowel with simultaneous gastrointestinal stromal tumor.转移性黑色素瘤穿孔至小肠并同时存在胃肠道间质瘤。
World J Gastroenterol. 2005 May 7;11(17):2687-9. doi: 10.3748/wjg.v11.i17.2687.
8
[Disseminated malignant melanoma, complicated with perforation of the small intestine and peritonitis].[播散性恶性黑色素瘤,并发小肠穿孔和腹膜炎]
Khirurgiia (Sofiia). 2003;59(4):44-5.
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Gastrointestinal metastases from malignant melanoma: report of a case.恶性黑色素瘤的胃肠道转移:一例报告
Surg Today. 2004;34(6):542-6. doi: 10.1007/s00595-004-2741-5.
10
Malignant melanoma: patterns of metastasis to the small bowel, reliability of imaging studies, and clinical relevance.恶性黑色素瘤:小肠转移模式、影像学检查的可靠性及临床意义。
Am J Gastroenterol. 2001 Aug;96(8):2392-400. doi: 10.1111/j.1572-0241.2001.04041.x.

肠道黑色素瘤:临床表现多种多样。

Intestinal melanoma: A broad spectrum of clinical presentation.

作者信息

Patti Rosalia, Cacciatori Matilde, Guercio Giovanni, Territo Valentina, Di Vita Gaetano

机构信息

Surgical Unit of the Department of Surgical and Oncological Science, University of Palermo, Italy.

出版信息

Int J Surg Case Rep. 2012;3(8):395-8. doi: 10.1016/j.ijscr.2012.03.033. Epub 2012 Apr 16.

DOI:10.1016/j.ijscr.2012.03.033
PMID:22659121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3376674/
Abstract

INTRODUCTION

Small intestine melanomas are rare and the most of them are metastases from primary cutaneous neoplasms.

PRESENTATION OF CASE

Below, we report two cases of small intestine metastatic melanoma with very different clinical presentation.

DISCUSSION

Still now, primary versus metastatic origin is often unclear. Small bowel melanoma is often asymptomatic. However, clinical picture can be various; it may occurs with non specific symptoms and signs of gastro-intetstinal involvement, like chronic abdominal pain, occult or gross bleeding and weight loss, or with an emergency picture due to intestinal intussusception, obstruction or, rarely, perforation.

CONCLUSION

Small bowel melanoma is rare and the diagnosis done late. Imaging techniques are recommended in order to obtain early diagnosis of gastrointestinal metastases.

摘要

引言

小肠黑色素瘤很罕见,其中大多数是原发性皮肤肿瘤的转移瘤。

病例报告

以下,我们报告两例小肠转移性黑色素瘤,其临床表现截然不同。

讨论

至今,原发性与转移性起源往往不明确。小肠黑色素瘤通常无症状。然而,临床表现可能多种多样;可能出现胃肠道受累的非特异性症状和体征,如慢性腹痛、隐匿性或显性出血及体重减轻,或因肠套叠、肠梗阻或很少见的穿孔而出现急症表现。

结论

小肠黑色素瘤罕见且诊断较晚。建议采用影像学技术以便早期诊断胃肠道转移瘤。