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肝肠内引流术在无胆管扩张的胰胆管合流异常儿童中的应用

Application of Embedding Hepaticojejunostomy in Children with Pancreaticobiliary Maljunction Without Biliary Dilatation.

机构信息

Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

出版信息

J Laparoendosc Adv Surg Tech A. 2022 Mar;32(3):336-341. doi: 10.1089/lap.2021.0634. Epub 2021 Nov 9.

Abstract

To investigate the effect of embedded hepaticojejunostomy in children with pancreaticobiliary maljunction (PBM) without biliary dilatation. The clinical data of 10 patients with nondilated PBM from February 2017 to July 2020 were retrospectively analyzed. Perioperative liver function indexes were compared. All patients were diagnosed by magnetic resonance cholangiopancreatography (MRCP) combined with intraoperative cholangiography. There were 5 cases of Komi type I and 5 cases of type II; the diameter of the common bile duct was 4-9 mm (median: 6 mm); and the length of the common channel was 5-15 mm (median: 9.25 mm). The procedure for one patient with common duct stones was converted to open surgery. Laparoscopic cholecystectomy, common bile duct resection, and embedded hepaticojejunostomy were successfully performed in all 10 cases. The average operation time was 225 ± 96.64 min, and the intraoperative blood loss was 2-5 mL. The mean time to oral intake was 3.5 ± 1.65 days (range: 2-5 days), and the mean hospitalization duration was 6.2 ± 2.44 days (range: 5-8 days). The differences in liver function indexes in the perioperative period were statistically significant ( < .05). The patients were followed-up for 13 to 54 months (median: 40 months). All patients grew well and there was no bile duct dilatation, calculus, or cirrhosis on B-ultrasound examinations. The clinical manifestations of nondilated PBM are often concealed, and preoperative MRCP was important for obtaining a diagnosis. Laparoscopic cholecystectomy, common bile duct resection, and embedded hepaticojejunostomy are feasible for treating nondilated PBM.

摘要

探讨无胆管扩张的先天性胰胆管合流异常(PBM)患儿行嵌入式胆肠吻合术的效果。回顾性分析 2017 年 2 月至 2020 年 7 月收治的 10 例无胆管扩张 PBM 患儿的临床资料,比较围手术期肝功能指标。所有患儿均经磁共振胰胆管成像(MRCP)联合术中胆道造影诊断。其中 Komi Ⅰ型 5 例,Ⅱ型 5 例;胆总管直径 4-9mm(中位数:6mm);共同胆管长度 5-15mm(中位数:9.25mm)。1 例胆总管结石患儿中转开腹手术。10 例患儿均顺利完成腹腔镜胆囊切除术、胆总管切除及嵌入式胆肠吻合术,手术时间平均 225±96.64min,术中出血量 2-5ml。术后开始经口进食时间平均 3.5±1.65d(2-5d),住院时间平均 6.2±2.44d(5-8d)。围手术期肝功能指标差异有统计学意义( < .05)。术后随访 13-54 个月(中位数:40 个月),患儿生长发育良好,B 超检查未见胆管扩张、结石及肝硬化。无胆管扩张的 PBM 临床表现常隐匿,术前 MRCP 对诊断有重要意义。腹腔镜胆囊切除术、胆总管切除及嵌入式胆肠吻合术适用于治疗无胆管扩张的 PBM。

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