[宜昌市成人带状疱疹发病率及其与早年饥荒暴露的关联研究]
[Study on the incidence of adult herpes zoster in Yichang city and its association with early-life famine exposure].
作者信息
Ding X, Jiang W, Hu Y H, Jiang J, Wu Y, Xu C Z, Wu Z Z, Yu Y F, Liu X J, Li G W, Yin D P
机构信息
School of Public Health, North China University of Science and Technology, Tangshan 063210,China.
Yichang Center for Disease Control and Prevention, Yichang 443003,China.
出版信息
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Nov 6;55(11):1328-1331. doi: 10.3760/cma.j.cn112150-20201110-01350.
Based on Yichang health big data platform, 850 608 patients from September 2018 to September 2019 were included in this study. According to the date of birth, the participants were divided into early childhood famine exposure group, fetal famine exposure group and non-famine exposure group. The incidence of adult herpes zoster (HZ) in Yichang city was analyzed, and the correlation between early life famine exposure and adult HZ was analyzed. In 2019, the crude incidence rate of adult HZ in Yichang was 6.83‰. The crude incidence rate of adult HZ in females (7.26‰) was higher than that in males (6.40‰). Compared with the non-famine exposure group, fetal famine exposure was associated with the incidence of adult HZ (=1.21; 95%: 1.01-1.45, =0.041). After stratification by sex, fetal famine exposure was only found to be associated with the onset of adult HZ in females (=1.28, 95%:1.02-1.61, =0.034).
基于宜昌市健康大数据平台，本研究纳入了2018年9月至2019年9月期间的850608例患者。根据出生日期，将参与者分为儿童期饥荒暴露组、胎儿期饥荒暴露组和非饥荒暴露组。分析了宜昌市成人带状疱疹（HZ）的发病率，并分析了生命早期饥荒暴露与成人HZ之间的相关性。2019年，宜昌市成人HZ的粗发病率为6.83‰。女性成人HZ的粗发病率（7.26‰）高于男性（6.40‰）。与非饥荒暴露组相比，胎儿期饥荒暴露与成人HZ的发病率相关（=1.21；95%：1.01-1.45，=0.041）。按性别分层后，仅发现胎儿期饥荒暴露与女性成人HZ的发病相关（=1.28，95%：1.02-1.61，=0.034）。
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