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直肠癌经腹会阴联合切除术:开腹、腹腔镜还是机器人手术?

Abdominoperineal Resection for Rectal Cancer: Open, Laparoscopic or Robotic Approach.

出版信息

Chirurgia (Bucur). 2021 Oct;116(5):573-582. doi: 10.21614/chirurgia.116.5.573.

DOI:10.21614/chirurgia.116.5.573
Abstract

The present study compares abdominoperineal resection (APR) performed by minimally invasive and open approach, regarding preoperative selection criteria, intraoperative and early postoperative aspects, in choosing the suitable technique performed by surgical teams with experience in both open and minimally invasive surgery (MIS). This is a retrospective study, conducted between 2008-2020. Two hundred thirty-three patients with APR performed for low rectal or anal cancer were included. The cohort was divided into two groups, depending on the surgical approach used: Minimally Invasive Surgery (laparoscopic and robotic procedures) and Open Surgery (OS). The perioperative characteristics were analyzed in order to identify the optimal approach and a possible selection criteria. We identified a high percentage of patients with a history of abdominal surgery in the open group (p = .0002). Intraoperative blood loss was significantly higher in the open group (p= .02), with an increased number of simultaneous resections (p = .041). The early postoperative outcome was marked by significantly lower morbidity in the MIS group (p = .005), with mortality recorded only in the open group (3 cases), in patients that associated severe comorbidities. The hystopathological results identified a significant number of patients with stage T2 in the MIS group (p= .037). Minimally invasive surgery provides a major advantage to APR, by avoiding an additional incision, the specimen being extracted through the perineal wound. The success of MIS APR seems to be assured by a good preoperative selection of the patients, alongside with experienced surgical teams in both open and minimally invasive rectal resections. The lack of conversion identified in robotic APR confirm the technical superiority over laparoscopic approach.

摘要

本研究比较了微创和开放两种途径进行的经腹会阴联合切除术(APR),比较了术前选择标准、术中及术后早期情况,旨在为有开放和微创手术经验的外科团队选择合适的技术。这是一项回顾性研究,于 2008 年至 2020 年进行。共纳入 233 例因低位直肠或肛门癌行 APR 的患者。该队列根据所使用的手术方法分为两组:微创外科(腹腔镜和机器人手术)和开放手术(OS)。分析围手术期特征,以确定最佳方法和可能的选择标准。我们发现,开放组中有较高比例的患者有腹部手术史(p =.0002)。开放组术中出血量明显较高(p=.02),同时进行的切除数量也较多(p =.041)。早期术后结果显示,微创组的发病率明显较低(p =.005),仅在开放组(3 例)记录到死亡率,这些患者合并严重合并症。组织病理学结果显示,微创组有相当数量的患者 T2 期(p=.037)。微创 APR 具有明显优势,避免了额外的切口,标本通过会阴切口取出。具有开放和微创直肠切除术经验的外科团队对患者进行良好的术前选择,确保了 MIS APR 的成功。机器人 APR 无转换,证实了其技术优于腹腔镜方法。

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