Bjerrum O W, Philip P, Pressler T, Tygstrup I
Cancer Genet Cytogenet. 1987 Sep;28(1):107-11. doi: 10.1016/0165-4608(87)90359-1.
Cytogenetic examination in a case of acute promyelocytic leukemia (FAB-M3) demonstrated a stem line with t(15;17) and a side line with t(2;17;15). This observation indicates either clonal evolution from the standard translocation or a de novo complicated translocation. Previous cases with three-way translocations in acute promyelocytic leukemia have been reviewed. Three-way translocations seem to occur with similar frequency in M2 and M3 types of acute myeloid leukemia and in chronic myelocytic leukemia.
