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Linkage analysis of the murine interferon alpha locus (Ifa) on chromosome 4.

作者信息

De Maeyer E, Dandoy F

出版信息

J Hered. 1987 May-Jun;78(3):143-6. doi: 10.1093/oxfordjournals.jhered.a110346.

DOI:10.1093/oxfordjournals.jhered.a110346
PMID:3475376
Abstract

We performed linkage analysis of the murine interferon alpha gene cluster, Ifa, with three different marker genes on chromosome 4: the major urinary protein locus (Mup-1), the brown locus (b) and the misty locus (m). The gene order (from centromere) with intervening percent recombination derived from a first three-point cross is Mup-1--13.6 (+/- 3.6)--Ifa--7.9 (+/- 2.8)--m and from a second three-point cross Mup-1--1.7 (+/- 1.7)--b--3.5 (+/- 2.4)--Ifa. The combined results indicate that the gene order, from the centromere, is Mup-1--b--Ifa--m.

摘要

相似文献

1
Linkage analysis of the murine interferon alpha locus (Ifa) on chromosome 4.
J Hered. 1987 May-Jun;78(3):143-6. doi: 10.1093/oxfordjournals.jhered.a110346.
2
Linkage analysis of the murine interferon-alpha locus on chromosome 4.小鼠4号染色体上α-干扰素基因座的连锁分析。
J Exp Med. 1984 Jul 1;160(1):294-302. doi: 10.1084/jem.160.1.294.
3
Linkage analysis of the murine mos proto-oncogene on chromosome 4.小鼠4号染色体上mos原癌基因的连锁分析。
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4
Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4.小鼠和人类同源染色体片段上基因的重排:α和β干扰素、α-1酸性糖蛋白-1和-2以及氨基乙酰丙酸脱水酶基因在小鼠4号染色体上的定位
Genetics. 1986 Dec;114(4):1239-55. doi: 10.1093/genetics/114.4.1239.
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The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization.小鼠干扰素-α(Ifa)基因座:通过原位杂交对物理图谱和连锁图谱的相关性分析
Cytogenet Cell Genet. 1986;41(2):101-6. doi: 10.1159/000132211.
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Segregation of restriction fragment length polymorphism in an interspecies cross of laboratory and wild mice indicates tight linkage of the murine IFN-beta gene to the murine IFN-alpha genes.在实验室小鼠和野生小鼠的种间杂交中,限制性片段长度多态性的分离表明鼠干扰素-β基因与鼠干扰素-α基因紧密连锁。
J Virol. 1985 Oct;56(1):216-20. doi: 10.1128/JVI.56.1.216-220.1985.
7
Interferon structural genes do not participate in quantitative regulation of interferon production by If loci as shown in C57BL/6 mice that are congenic with BALB/c mice at the alpha interferon gene cluster.干扰素结构基因并不参与If基因座对干扰素产生的定量调控,这在α干扰素基因簇与BALB/c小鼠同源的C57BL/6小鼠中得到了证实。
J Virol. 1986 Jun;58(3):743-7. doi: 10.1128/JVI.58.3.743-747.1986.
8
Mapping the structural genes coding for the major urinary proteins in the mouse: combined use of recombinant inbred strains and somatic cell hybrids.绘制小鼠主要尿蛋白编码结构基因图谱:重组近交系与体细胞杂种的联合应用
Proc Natl Acad Sci U S A. 1982 Feb;79(4):1220-4. doi: 10.1073/pnas.79.4.1220.
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The physical separation of Lps and Ifa loci in BXH recombinant inbred mice.BXH重组近交系小鼠中Lps和Ifa基因座的物理分离。
J Immunol. 1989 Nov 1;143(9):3001-6.
10
Conserved linkage of soluble aconitase and galactose-1-phosphate uridyl transferase in mouse and man: assignment of these genes to mouse chromosome 4.小鼠和人类中可溶性乌头酸酶与1-磷酸半乳糖尿苷酰转移酶的保守连锁:将这些基因定位到小鼠4号染色体上。
Cytogenet Cell Genet. 1982;34(4):271-81. doi: 10.1159/000131817.

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