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柏林夏里特大学医院妇科难民妇女的围产期数据与德国联邦分析结果的比较

Perinatal Data of Refugee Women from the Gynaecology Department of Charité University Hospital Berlin Compared with German Federal Analysis.

作者信息

Ammoura Ola, Sehouli Jalid, Kurmeyer Christine, Richter Rolf, Kutschke Nadja, Henrich Wolfgang, Inci Melisa Guelhan

机构信息

Charité - Universitätsmedizin Berlin, Klinik für Gynäkologie, Campus Virchow-Klinikum, Berlin, Germany.

Charité - Universitätsmedizin Berlin, Frauen- und Gleichstellungsbeauftragte, Berlin, Germany.

出版信息

Geburtshilfe Frauenheilkd. 2021 Jul 21;81(11):1238-1246. doi: 10.1055/a-1397-6888. eCollection 2021 Nov.

Abstract

The aim of this study was to record the perinatal data of refugee women at Charité Hospital, Berlin, and to evaluate possible differences in pre-, peri- and postnatal outcomes compared with indigenous women. All pregnant women who gave birth in the period from 1 January 2014 to 30 September 2017 and were registered at least once in the hospital as "refugee" were included in the analysis. The data recorded from the refugee women were compared with the perinatal data of the German Federal obstetric analysis for the year 2016, which was published by the IQTIG (Institut für Qualitätssicherung und Transparenz im Gesundheitswesen [Institute for Quality Assurance and Transparency in Healthcare]). The analysis comprised 907 refugee women and 928 infants (21 twin pregnancies). Pregnant refugee women were significantly younger than the pregnant women from the Federal analysis (birth before the age of 30: 66 vs. 41%, p < 0.001, RR: 1.6, 95% CI: 62.9 - 69.2). They had a history both of more pregnancies (≥ 3 pregnancies: 29.4 vs. 13.4%, p < 0.001, RR: 2.2, 95% CI: 26.4 - 32.5) and of more miscarriages (> 2 miscarriages: 9.7 vs. 5.9%, p < 0.001, RR: 1.6, 95% CI: 7.9 - 11.8) and more often had a history of suffering from psychological stress (11.1 vs. 4.1%, p < 0.001, RR: 2.70, 95% CI: 9.2 - 13.4). There were more premature births (10.3 vs. 3.0%, p < 0.001, RR: 3.36, 95% CI: 8.4 - 12.4), post-term pregnancies (8.5 vs. 0.5%, p < 0.001, RR: 15.4, 95% CI: 6.7 - 10.5), and cases of postpartum anaemia (28.7 vs. 22.0%, p < 0.001, RR: 1.30, 95% CI: 25.7 - 31.7) and puerperal endometritis (1 vs. 0.2%, p = 0.006, RR: 4.3, 95% CI: 0.5 - 1.9) compared with the Federal analysis. The neonatal outcome showed an increased rate of hypotrophy (11 vs. 7%, p < 0.001, RR: 1.6, 95% CI: 9.1 - 13.2), more stillbirths (0.7 vs. 0.2%, p = 0.006, RR: 3, 95% CI: 0.2 - 1.4) and increased congenital malformations (2.8 vs. 0.4%, p < 0.001, RR: 3, 95% CI: 0.2 - 1.4). Both refugee women and their infants showed significant differences. Despite the average younger age of the pregnant refugee women, the rates of premature birth and stillbirth and congenital malformations were significantly more frequent. More intensive antenatal screening with differentiated foetal organ diagnostics including psychosomatic care could contribute to early identification and prompt diagnosis. As regards the postpartum anaemia and puerperal endometritis, which occur more often in refugee women, midwife engagement and an improvement in the living situation in homes and accommodation facilities could be of great importance.

摘要

本研究的目的是记录柏林夏里特医院难民妇女的围产期数据,并评估与本地妇女相比,她们在产前、产时和产后结局方面可能存在的差异。分析纳入了2014年1月1日至2017年9月30日期间在该医院分娩且至少有一次登记为“难民”的所有孕妇。将难民妇女记录的数据与德国联邦2016年产科分析的围产期数据进行比较,该数据由IQTIG(医疗卫生质量保证与透明度研究所)发布。分析包括907名难民妇女和928名婴儿(21例双胎妊娠)。怀孕的难民妇女比联邦分析中的孕妇明显年轻(30岁前分娩:66%对41%,p<0.001,RR:1.6,95%CI:62.9 - 69.2)。她们有更多的妊娠史(≥3次妊娠:29.4%对13.4%,p<0.001,RR:2.2,95%CI:26.4 - 32.5)和更多的流产史(>2次流产:9.7%对5.9%,p<0.001,RR:1.6,95%CI:7.9 - 11.8),并且更常有心理压力史(11.1%对4.1%,p<0.001,RR:2.70,95%CI:9.2 - 13.4)。与联邦分析相比,早产(10.3%对3.0%,p<0.001,RR:3.36,95%CI:8.4 - 12.4)、过期妊娠(8.5%对0.5%,p<0.001,RR:15.4,95%CI:6.7 - 10.5)、产后贫血病例(28.7%对22.0%,p<0.001,RR:1.30,95%CI:25.7 - 31.7)和产褥期子宫内膜炎(1%对0.2%,p = 0.006,RR:4.3,95%CI:0.5 - 1.9)更多。新生儿结局显示发育迟缓率增加(11%对7%,p<0.001,RR:1.6,95%CI:9.1 - 13.2)、死产更多(0.7%对0.2%,p = 0.006,RR:3,95%CI:0.2 - 1.4)以及先天性畸形增加(2.8%对0.4%,p<0.001,RR:3,95%CI:0.2 - 1.4)。难民妇女及其婴儿均显示出显著差异。尽管怀孕的难民妇女平均年龄较小,但早产、死产和先天性畸形的发生率明显更高。更强化的产前筛查,包括采用差异化的胎儿器官诊断以及身心护理,可能有助于早期识别和及时诊断。至于难民妇女中更常出现的产后贫血和产褥期子宫内膜炎,助产士的参与以及改善家庭和住宿设施中的生活状况可能非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0365/8568502/431732072da5/10-1055-a-1397-6888-igf01.jpg

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