Sasaki Shu, Takahashi Makoto, Hayashi Tatsuya, Morita Yasuhiro, Namiki Shin, Itagaki Shingo
Department of Surgery, Tokyo Metropolitan Tama Medical Center, Fuchu-shi, Tokyo 183-8524, Japan.
Department of Gastroenterology and Hepatology, Tokyo Metropolitan Tama Medical Center, Fuchu-shi, Tokyo 183-8524, Japan.
Mol Clin Oncol. 2021 Dec;15(6):259. doi: 10.3892/mco.2021.2421. Epub 2021 Oct 19.
Indocyanine green (ICG) fluorescence imaging is useful for the intraoperative detection of the peritoneal dissemination of hepatocellular carcinoma (HCC). However, in laparoscopic surgery, disseminations cannot be accurately identified unless the camera lens is positioned close to the lesion. The present study describes a case of HCC dissemination in which the lesions were accurately identified by combining intraoperative fluoroscopy with ICG fluorescence imaging. A 76-year-old male was diagnosed with HCC dissemination. Computed tomography revealed a 9-mm disseminated nodule near the gallbladder. Although transarterial chemoembolization had also been used to treat this lesion, chemoembolization was technically difficult to perform. Therefore, a coil was placed around the lesion to serve as an intraoperative landmark for later laparoscopic resection. Given the potential difficulty of detecting the lesion during laparoscopic surgery, ICG fluorescence imaging was used to determine the approximate location of the dissemination. The lesion exhibited strong fluorescence, which facilitated its complete resection.
吲哚菁绿（ICG）荧光成像有助于在术中检测肝细胞癌（HCC）的腹膜播散。然而，在腹腔镜手术中，除非将摄像头镜头靠近病变部位，否则无法准确识别播散灶。本研究描述了一例HCC播散病例，其中通过术中荧光透视与ICG荧光成像相结合准确识别了病变。一名76岁男性被诊断为HCC播散。计算机断层扫描显示胆囊附近有一个9毫米的播散结节。尽管也曾使用经动脉化疗栓塞术治疗该病变，但化疗栓塞术在技术上难以实施。因此，在病变周围放置了一个线圈，作为后期腹腔镜切除术中的术中标志物。鉴于腹腔镜手术中检测病变可能存在困难，使用ICG荧光成像来确定播散灶的大致位置。病变呈现强烈荧光，这有助于其完整切除。
