Pettersson Samuel D, Ali Shan, Burmaka Pavlo, Fercho Justyna, Szmuda Tomasz, Abuhaimed Ahmed, Alotaibi Yazeed, Słoniewski Paweł, Krakowiak Michał
Department of Neurosurgery, Scientific Circle of Neurology and Neurosurgery, Pomeranian Voivodeship, Poland.
Department of Neurosurgery, Medical University of Gdansk, Gdansk, Pomeranian Voivodeship, Poland.
Surg Neurol Int. 2021 Oct 19;12:530. doi: 10.25259/SNI_723_2021. eCollection 2021.
Incomplete resection of neurenteric cysts (NCs) has been associated with increased recurrence rates in patients compared to complete resection (CR) and information on intracranial NCs appearance on diagnostic imaging is scarce. We sought to identify factors associated with CR and provide the largest up-to-date review of NCs appearances on various diagnostic images.
Data from Medline, EMBASE, and Web of Science were extracted. Univariate and multivariate logistic regression models were used to analyze factors associated with CR.
A total of 120 publications reporting 162 original cases on posterior fossa NCs met the inclusion criteria for analysis. Eighty-nine (55.6%) of the patients were female, the mean (SD) age of the patients' during operation was 34.3 (16.9) years, and CR was achieved in 98 (60%) of patients. Univariate analysis identified male sex as a statistically significant predictor for complete reaction (OR 2.13, 95% Cl 1.10-4.11, = 0.02). The retrosigmoid approach (OR 1.89, 95% Cl 0.98-3.63, = 0.06), far lateral approach (OR 0.46, 95% Cl 0.21-1.02, = 0.06), and pediatric patient (OR 2.45, 95% Cl 0.94-6.56, = 0.07) may be possible predictors for CR, however, they were not statistically significant. NCs are mainly hypodense on CT (32 [61.5%]), varied greatly in intensity on T1WI, hyperintense on T2WI magnetic resonance imaging (98 [67.1%]), and hyperintense on fluid-attenuated inversion recovery (17 [63.0%]).
We recommend utilizing various diagnostic imaging tests to help reduce misdiagnoses when identifying intracranial NCs. For patient safety, CR should be achieved when possible, to reduce risk of additional operations due to recurrence.
与完全切除（CR）相比，神经肠囊肿（NCs）不完全切除与患者复发率增加相关，且关于诊断性影像学上颅内NCs表现的信息较少。我们试图确定与CR相关的因素，并对各种诊断图像上NCs的表现进行最新的、规模最大的综述。
从Medline、EMBASE和科学网提取数据。使用单因素和多因素逻辑回归模型分析与CR相关的因素。
共有120篇报告后颅窝NCs 162例原始病例的出版物符合分析纳入标准。89例（55.6%）患者为女性，患者手术时的平均（标准差）年龄为34.3（16.9）岁，98例（60%）患者实现了CR。单因素分析确定男性是完全反应的统计学显著预测因素（OR 2.13，95%CI 1.10-4.11，P = 0.02）。乙状窦后入路（OR 1.89，95%CI 0.98-3.63，P = 0.06）、远外侧入路（OR 0.46，95%CI 0.21-1.02，P = 0.06）和儿科患者（OR 2.45，95%CI 0.94-6.56，P = 0.07）可能是CR的预测因素，然而，它们无统计学显著性。NCs在CT上主要为低密度（32例[61.5%]），在T1WI上强度差异很大，在T2WI磁共振成像上为高信号（98例[67.
