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支持细胞样囊腺瘤保留睾丸手术的首例报告:病例介绍及文献复习

First report of testis-sparing surgery for sertoliform cystadenoma: case presentation and review of literature.

作者信息

Rahota Razvan-George, Ploussard Guillaume, Gautier Jean-Romain, Almeras Christophe, Ducoin Henri, Tollon Christophe, Assoun Jacques, Loison Guillaume, Beauval Jean-Baptiste, Salin Ambroise

机构信息

Department of Urology La Croix du Sud Hospital Quint Fonsegrives France.

Department of Pathology La Croix du Sud Hospital Quint Fonsegrives France.

出版信息

IJU Case Rep. 2021 Sep 7;4(6):425-428. doi: 10.1002/iju5.12366. eCollection 2021 Nov.

DOI:10.1002/iju5.12366
PMID:34755074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8560452/
Abstract

INTRODUCTION

Sertoliform cystadenoma is a very rare, benign lesion of the rete-testis difficult to distinguish from other malignancies of the testicle.

CASE PRESENTATION

We present the case of a 42-year-old male who presented with a right testicular mass, asymptomatic for 1 year. Clinical examination revealed a palpable, painless, and well-delimited right testicular superior pole nodule. Testicular ultrasound confirmed the nodule, whereas serum tumoral markers were normal. The patient underwent inguinal partial orchiectomy. Intraoperative excisional biopsy and frozen section pathology were performed, reporting undetermined tumoral origin with negative surgical margins. Ischemia time was 12 minutes. The final pathology report showed a Sertoliform cystadenoma of rete testis, with immunomorphology positive for AE1, CK7, and negative surgical margins.

CONCLUSION

To our knowledge, this is the first report of testicular sparing surgery for Sertoliform cystadenoma, a very rare benign tumor of rete testis. All previously reported cases were managed by radical inguinal orchidectomy.

摘要

引言

睾丸网管状囊腺瘤是一种非常罕见的睾丸网良性病变,很难与睾丸的其他恶性肿瘤区分开来。

病例报告

我们报告一例42岁男性,右侧睾丸肿块1年无症状。临床检查发现右侧睾丸上极可触及、无痛且边界清晰的结节。睾丸超声证实了该结节,而血清肿瘤标志物正常。患者接受了腹股沟部分睾丸切除术。术中进行了切除活检和冰冻切片病理检查,报告肿瘤起源不明,手术切缘阴性。缺血时间为12分钟。最终病理报告显示为睾丸网管状囊腺瘤,免疫形态学显示AE1、CK7阳性,手术切缘阴性。

结论

据我们所知,这是首例针对睾丸网管状囊腺瘤(一种非常罕见的睾丸网良性肿瘤)的保留睾丸手术报告。所有先前报道的病例均通过根治性腹股沟睾丸切除术进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/b7ab73b2367a/IJU5-4-425-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/f914945c6532/IJU5-4-425-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/81cba9653756/IJU5-4-425-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/b7ab73b2367a/IJU5-4-425-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/f914945c6532/IJU5-4-425-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/81cba9653756/IJU5-4-425-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7567/8560452/b7ab73b2367a/IJU5-4-425-g003.jpg

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Editorial Comment to First report of testis-sparing surgery for sertoliform cystadenoma: case presentation and review of literature .
IJU Case Rep. 2021 Sep 20;4(6):428. doi: 10.1002/iju5.12378. eCollection 2021 Nov.

本文引用的文献

1
The Morphologic Spectrum of Sertoliform Cystadenoma of the Rete Testis: A Series of 15 Cases.睾丸网索状囊腺瘤的形态学谱系:15 例系列研究。
Am J Surg Pathol. 2018 Feb;42(2):141-149. doi: 10.1097/PAS.0000000000000997.
2
Sertoliform Cystadenoma of the Rete Testis: Report of a Case and Review of the Literature.睾丸网的支持细胞样囊腺瘤:1例报告及文献复习
Int J Surg Pathol. 2017 Sep;25(6):555-558. doi: 10.1177/1066896917704304. Epub 2017 Apr 16.
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Reliability of Frozen Section Examination in a Large Cohort of Testicular Masses: What Did We Learn?
大量睾丸肿块队列中冰冻切片检查的可靠性:我们学到了什么?
Clin Genitourin Cancer. 2017 Aug;15(4):e689-e696. doi: 10.1016/j.clgc.2017.01.012. Epub 2017 Feb 1.
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Guidelines on Testicular Cancer: 2015 Update.睾丸癌诊疗指南:2015 年更新版
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An unexpected finding of a rare intrascrotal lesion: the sertoliform cystadenoma of the rete testis.罕见阴囊内病变的意外发现:睾丸网的支持细胞样囊腺瘤。
BMJ Case Rep. 2013 Feb 20;2013:bcr2012008439. doi: 10.1136/bcr-2012-008439.
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Sertoliform cystadenoma: a rare benign tumour of the rete testis.支持细胞瘤性囊腺瘤:一种罕见的睾丸网良性肿瘤。
Diagn Pathol. 2013 Feb 14;8:23. doi: 10.1186/1746-1596-8-23.
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Unusual scrotal pathology: an overview.异常阴囊病理学概述。
Nat Rev Urol. 2009 Sep;6(9):491-500. doi: 10.1038/nrurol.2009.149. Epub 2009 Aug 11.
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Morphological approach to tumours of the testis and paratestis.睾丸及睾丸旁肿瘤的形态学研究方法
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