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机器人辅助根治性膀胱切除术后结肠内膀胱癌早期复发:在密集剂量甲氨蝶呤、长春碱、阿霉素和顺铂治疗后消失

Early recurrence of bladder cancer in the colon after robot-assisted radical cystectomy: Disappearance following dose-dense methotrexate, vinblastine, doxorubicin and cisplatin treatment.

作者信息

Noda Michio, Nakamura Masaki, Kawai Taketo, Sato Yusuke, Yamada Yuta, Akiyama Yoshiyuki, Yamada Daisuke, Suzuki Motofumi, Kume Haruki

机构信息

Department of Urology Mitsui Memorial Hospital Japan.

Department of Urology Graduate School of Medicine The University of Tokyo Japan.

出版信息

IJU Case Rep. 2021 Sep 8;4(6):429-432. doi: 10.1002/iju5.12370. eCollection 2021 Nov.

Abstract

INTRODUCTION

The popularity of robot-assisted radical cystectomy over open radical cystectomy has been increasing because the former, a minimally invasive surgery, contributes to earlier recovery and shorter hospitalization. However, atypical recurrences may be more frequent after robot-assisted radical cystectomy than after open radical cystectomy. We report a case of an atypical early recurrence of bladder cancer including the descending colon.

CASE PRESENTATION

A 70-year-old Japanese man underwent robot-assisted radical cystectomy for muscle-invasive bladder cancer. Four months later, he was hospitalized for severe anemia (hemoglobin, 5.1 g/dL). Colonoscopy revealed a 4-cm submucosal oozing tumor in the descending colon. Computed tomography revealed multiple recurrent lesions including recurrence in the descending colon, all of which disappeared completely after chemotherapy with six cycles of dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin.

CONCLUSION

We encountered a rare case of an atypical recurrence of bladder cancer in the colon after robot-assisted radical cystectomy.

摘要

引言

机器人辅助根治性膀胱切除术相较于开放性根治性膀胱切除术越来越受欢迎,因为前者作为一种微创手术,有助于更早康复和缩短住院时间。然而,机器人辅助根治性膀胱切除术后非典型复发可能比开放性根治性膀胱切除术后更频繁。我们报告一例包括降结肠在内的膀胱癌非典型早期复发病例。

病例介绍

一名70岁日本男性因肌层浸润性膀胱癌接受了机器人辅助根治性膀胱切除术。四个月后,他因严重贫血(血红蛋白5.1g/dL)住院。结肠镜检查发现降结肠有一个4厘米的黏膜下渗血肿瘤。计算机断层扫描显示多处复发灶,包括降结肠复发,在接受六个周期剂量密集型甲氨蝶呤、长春碱、阿霉素和顺铂化疗后,所有病灶完全消失。

结论

我们遇到了一例机器人辅助根治性膀胱切除术后罕见的结肠癌非典型复发病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01fa/8560432/264d315021f0/IJU5-4-429-g001.jpg

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