Suppr超能文献

Topics in AAV integration come front and center at ASGCT AAV Integration Roundtable.

作者信息

Sabatino Denise E, McCarty Douglas M

机构信息

The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; Division of Hematology, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Durham, NC, USA.

出版信息

Mol Ther. 2021 Dec 1;29(12):3319-3320. doi: 10.1016/j.ymthe.2021.10.024. Epub 2021 Nov 10.

Abstract
摘要

相似文献

1
Topics in AAV integration come front and center at ASGCT AAV Integration Roundtable.
Mol Ther. 2021 Dec 1;29(12):3319-3320. doi: 10.1016/j.ymthe.2021.10.024. Epub 2021 Nov 10.
2
Site-specific integration of adeno-associated virus-based plasmid vectors in lipofected HeLa cells.
Virology. 2000 Mar 15;268(2):391-401. doi: 10.1006/viro.1999.0122.
3
Integration of adeno-associated virus (AAV) and recombinant AAV vectors.
Annu Rev Genet. 2004;38:819-45. doi: 10.1146/annurev.genet.37.110801.143717.
4
Adeno-associated virus vector integration junctions.
J Virol. 1997 Nov;71(11):8429-36. doi: 10.1128/JVI.71.11.8429-8436.1997.
6
Adeno-associated virus vector integration.
Curr Opin Mol Ther. 2009 Aug;11(4):442-7.
7
AAV vectors for the nucleolus.
Mol Ther. 2012 Oct;20(10):1842-3. doi: 10.1038/mt.2012.193.

引用本文的文献

1
Reversion of metabolic dysfunction-associated steatohepatitis by skeletal muscle-directed FGF21 gene therapy.
Mol Ther. 2024 Dec 4;32(12):4285-4302. doi: 10.1016/j.ymthe.2024.10.023. Epub 2024 Oct 28.
3
Ectopic clotting factor VIII expression and misfolding in hepatocytes as a cause for hepatocellular carcinoma.
Mol Ther. 2022 Dec 7;30(12):3542-3551. doi: 10.1016/j.ymthe.2022.10.004. Epub 2022 Oct 14.
4
Adeno-associated virus-mediated expression of activated factor V (FVa) for hemophilia phenotypic correction.
Front Med (Lausanne). 2022 Aug 5;9:880763. doi: 10.3389/fmed.2022.880763. eCollection 2022.
5
Gene Therapy: Will the Promise of Optimizing Lung Allografts Become Reality?
Front Immunol. 2022 Jul 1;13:931524. doi: 10.3389/fimmu.2022.931524. eCollection 2022.
6
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective.
Mol Ther. 2022 Aug 3;30(8):2646-2663. doi: 10.1016/j.ymthe.2022.06.004. Epub 2022 Jun 10.

本文引用的文献

1
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells.
Nat Biotechnol. 2021 Jan;39(1):47-55. doi: 10.1038/s41587-020-0741-7. Epub 2020 Nov 16.
2
Recombinant Adeno-Associated Viral Integration and Genotoxicity: Insights from Animal Models.
Hum Gene Ther. 2017 Apr;28(4):314-322. doi: 10.1089/hum.2017.009.
3
Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.
J Clin Invest. 2015 Feb;125(2):870-80. doi: 10.1172/JCI79213. Epub 2015 Jan 20.
4
Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.
Gene Ther. 2001 Sep;8(17):1343-6. doi: 10.1038/sj.gt.3301541.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验