Tidsskr Nor Laegeforen. 2021 Nov 8;141(16). doi: 10.4045/tidsskr.21.0333. Print 2021 Nov 9.
The prevalence of restless legs syndrome (RLS) among adults in the general population is around 5-10 %. Few studies have been conducted on the prevalence among patients who consult their general practitioner. There are also few studies on associations between RLS and other common complaints such as irritable bowel syndrome (IBS), chronic fatigue (CF) and chronic muscle and back pain (CMBP).
The study was conducted as a questionnaire survey at medical offices in Southern and Western Norway in the autumn of 2017 and spring of 2018, when patients waiting to see their general practitioner (GP) were invited to participate. A total of 2 634 people took part (62.2 % women, average age 49.6 years). The response rate was 86.8 %. Restless legs syndrome (RLS) was defined on the basis of international criteria. Associations between RLS and IBS, CF and CMBP were analysed by means of chi-squared tests and logistic regression.
The proportion of patients with RLS was 14.3 %. Of the patients with RLS, 44.8 % reported that their symptoms were moderately to very distressing, and 85.8 % that they did not use medication for it. The proportion of patients with RLS was significantly higher among patients with IBS (21.8 % versus 13.6 %, p = 0.009), CF (18.2 % versus 13.1 %, p = 0.003) and CMBP (23.2 % versus 12.2 %, p < 0.0005). GPs should be aware that many patients have RLS and that the condition is associated with other common complaints.
普通人群中成年人不安腿综合征（RLS）的患病率约为 5-10%。针对向全科医生就诊的患者中RLS 的患病率进行的研究较少。关于 RLS 与其他常见疾病（如肠易激综合征（IBS）、慢性疲劳（CF）和慢性肌肉和背痛（CMBP））之间的关联也很少有研究。
该研究于 2017 年秋季和 2018 年春季在挪威南部和西部的医疗办公室进行问卷调查，当时邀请等待看全科医生（GP）的患者参与。共有 2634 人参加（62.2%为女性，平均年龄 49.6 岁），应答率为 86.8%。根据国际标准定义 RLS。采用卡方检验和逻辑回归分析 RLS 与 IBS、CF 和 CMBP 之间的关系。
RLS 患者的比例为 14.3%。在 RLS 患者中，44.8%报告其症状中度至非常困扰，85.8%的患者未使用药物治疗。与 IBS（21.8%比 13.6%，p=0.009）、CF（18.2%比 13.1%，p=0.003）和 CMBP（23.2%比 12.2%，p<0.0005）患者相比，RLS 患者的比例明显更高。全科医生应注意到，许多患者患有 RLS，并且该疾病与其他常见疾病相关。
