Prakash Sanjay, Prakash Anurag
Neurolgy, Smt BK Shah Medical Institute and Research Centre, Vadodara, Gujarat, India
Parul University Parul Institute of Medical Sciences & Research, Vadodara, Gujarat, India.
BMJ Case Rep. 2021 Mar 24;14(3):e240686. doi: 10.1136/bcr-2020-240686.
In addition to the legs, restless legs syndrome (RLS) affects various other parts of the body, including the arms, abdomen, face, head-neck, oral cavity, genital area and bladder. RLS is also associated with several comorbid conditions, including irritable bowel syndrome (IBS). We are reporting two cases of RLS who also had IBS, fulfilling the Rome IV criteria. The administration of levodopa and dopamine agonists provided a complete improvement in both IBS and RLS. Review of the literature suggest that the clinical semiology and clinical pattern of IBS (urge to defaecate, abdominal pain, abdominal distension, bloating, disturbed sleep and circadian rhythm) simulate the semiology and pattern of RLS. Similarities are also noted in the associated comorbid conditions, effective drugs and proposed hypotheses for both clinical syndromes. We hypothesise that RLS may affect intestine, and IBS-like symptoms in a subset of patients with RLS may be the part of RLS symptoms complex.
除了腿部，不宁腿综合征（RLS）还会影响身体的其他各个部位，包括手臂、腹部、面部、头颈、口腔、生殖器区域和膀胱。RLS还与多种合并症有关，包括肠易激综合征（IBS）。我们报告了两例同时患有IBS且符合罗马IV标准的RLS病例。左旋多巴和多巴胺激动剂的使用使IBS和RLS均得到了完全改善。文献回顾表明，IBS的临床症状学和临床模式（排便冲动、腹痛、腹胀、腹部胀气、睡眠障碍和昼夜节律紊乱）与RLS的症状学和模式相似。在相关合并症、有效药物以及针对这两种临床综合征提出的假设中也发现了相似之处。我们推测RLS可能会影响肠道，并且RLS患者亚组中类似IBS的症状可能是RLS症状复合体的一部分。
