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手术治疗复杂急性阑尾炎患者行扩大切除术的术前预测因素。

Preoperative predictors of extended resection in patients with complicated acute appendicitis undergoing surgery.

机构信息

Division of Digestive Surgery, Ehime Prefectural Central Hospital, Ehime, Japan.

Division of General Surgery, Ehime Prefectural Imabari Hospital, Ehime, Japan.

出版信息

J Med Invest. 2021;68(3.4):334-341. doi: 10.2152/jmi.68.334.

DOI:10.2152/jmi.68.334
PMID:34759155
Abstract

Background : Appendectomy can be challenging and occasionally converted to extensive resection for complicated appendicitis. However, optimal treatment strategies can be developed using preoperative risk assessment. Thus, we aimed to investigate the preoperative predictors of extensive resection in complicated appendicitis patients undergoing surgery. Materials and methods : In total, 173 complicated appendicitis patients undergoing surgery between 2014 and 2019 were classified into the appendectomy (n = 153) or extensive resection (n = 20) groups. Clinicopathological factors and surgical outcomes were compared between groups. Results : Extensive resection was performed in 20 of 173 complicated appendicitis patients (11.5%). The rates of having defects in the wall structure at the appendix root on computed tomography images were significantly higher, and the duration from onset to surgery was significantly longer in the extensive resection group. Significant differences were found in operative duration, blood loss and postoperative hospitalization, but none in the incidence of postoperative complications between groups. Multivariate analyses showed that defects in the wall structure at the appendix root and five days or longer from onset were identified as independent predictors of extensive resection. Conclusions : Defects in the wall structure at the appendix root and five days or longer from onset predict extensive resection performance in complicated appendicitis patients. J. Med. Invest. 68 : 334-341, August, 2021.

摘要

背景

阑尾切除术具有挑战性,在某些情况下,复杂阑尾炎可能需要转为广泛切除术。然而,通过术前风险评估,可以制定出最佳的治疗策略。因此,我们旨在研究接受手术治疗的复杂阑尾炎患者中,术前哪些因素与广泛切除术相关。

方法

共纳入 2014 年至 2019 年间 173 例接受手术治疗的复杂阑尾炎患者,分为行阑尾切除术(n=153)或广泛切除术(n=20)的两组。比较两组的临床病理因素和手术结果。

结果

173 例复杂阑尾炎患者中有 20 例行广泛切除术(11.5%)。广泛切除术组的阑尾根部结构缺陷在 CT 图像上的检出率明显更高,发病至手术的时间明显更长。手术时间、出血量和术后住院时间存在显著差异,但术后并发症发生率无差异。多因素分析显示,阑尾根部结构缺陷和发病后 5 天或更长时间是广泛切除术的独立预测因素。

结论

阑尾根部结构缺陷和发病后 5 天或更长时间提示复杂阑尾炎患者需要进行广泛切除术。

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