Martz Nicolas, Benziane-Ouaritini Nicolas, Gautier Mathieu, Brenot-Rossi Isabelle, Montagne Lucile, Salem Naji, Bodokh Yohan, Hannoun-Levi Jean-Michel
Department of Radiation Therapy, Antoine Lacassagne Cancer Center and University of Nice-Sophia, University Cote d'Azur, Nice, France.
Department of Radiotherapy, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
J Contemp Brachytherapy. 2021 Oct;13(5):593-597. doi: 10.5114/jcb.2021.109754. Epub 2021 Oct 6.
The origin of penile metastases is in 70% of cases from primary pelvic cancers (genitourinary and recto-sigmoid primary tumors). The prognosis is poor and it is often associated with synchronous bone metastases at the time of diagnosis. We present the case of a 61-year-old patient who developed a penile induration 7 years after radical prostatectomy followed by adjuvant external beam radiation therapy for high-risk prostatic adenocarcinoma. Biopsies confirmed the metastatic localization and a detailed assessment failed to find any further remote lesions. Faced with this penile oligometastatic prostate cancer, we proposed an ablative treatment based on interstitial multi-catheter high-dose rate brachytherapy. At the six-month follow-up, clinical examination and Ga-PSMA-11-PET confirmed a complete response of the penile tumor without new lesion at a distance.
阴茎转移瘤的起源在70%的病例中来自原发性盆腔癌（泌尿生殖系统和直肠乙状结肠原发性肿瘤）。预后较差，且在诊断时常伴有同步骨转移。我们报告一例61岁患者，该患者在根治性前列腺切除术后7年出现阴茎硬结，随后因高危前列腺腺癌接受辅助外照射放疗。活检证实为转移灶，详细评估未发现任何其他远处病变。面对这种阴茎寡转移前列腺癌，我们提出了一种基于多导管间质高剂量率近距离放疗的消融治疗方案。在六个月的随访中，临床检查和Ga-PSMA-11-PET证实阴茎肿瘤完全缓解，无远处新病灶。
