Kamrani Ghodsieh, Nikbakhsh Novin, Hosseini Akarm, Ghorbani Hossein, Arefisigaroudi Niloufar, Davarian Ali
Department of Pathology, Cancer Research Institute, Babol University of Medical Science, Babol , Iran.
Department of surgery, Cancer Research Institute, Babol University of Medical Sciences, Babol , Iran.
Caspian J Intern Med. 2021;12(Suppl 2):S444-S446. doi: 10.22088/cjim.12.0.444.
Mucinous cystadenocarcinoma is a relatively uncommon histological subtype of breast cancer that is a cystic form of papillary mucinous carcinoma. It is regularly negative for estrogen and progesterone receptors and it is most often diagnosed in older than 55-60 years old. The incidence of breast mucinous cystadenocarcinoma is about 1-6% of primary breast cancers. Here, we present a case of breast mucinous cystadenocarcinoma of left breast in a 69-year-old female which is positive for estrogen and progesterone receptors.
In this article, we describe a case of a-69-year-old female with a painful mass in her left breast. Based on intraoperative pathology consult, neoplastic tissue mostly floating in mucinous lakes with invasion to surrounding stroma was seen. Immunohistochemistry profile showed positive estrogen and progesterone receptors and negative for HER2.
Mucinous cystadenocarcinoma of breast is typically triple negative for hormone receptors. But ER and PR positive variant of this tumor is rare, giving the chance of a better prognosis for the patient with hormonal therapy.
黏液性囊腺癌是一种相对罕见的乳腺癌组织学亚型，是乳头状黏液癌的囊性形式。它通常对雌激素和孕激素受体呈阴性，最常发生于55 - 60岁以上的人群。乳腺黏液性囊腺癌的发病率约占原发性乳腺癌的1% - 6%。在此，我们报告一例69岁女性左乳腺黏液性囊腺癌，该病例雌激素和孕激素受体呈阳性。
在本文中，我们描述了一例69岁女性，其左乳有一疼痛性肿块。根据术中病理会诊，可见肿瘤组织大多漂浮在黏液湖中，并侵犯周围间质。免疫组化结果显示雌激素和孕激素受体呈阳性，HER2呈阴性。
乳腺黏液性囊腺癌通常激素受体为三阴性。但该肿瘤雌激素受体和孕激素受体阳性的变异型罕见，这为激素治疗的患者带来了更好的预后机会。
