Prieto F, Badía L, Gomis F, Dieguez L
Cancer Genet Cytogenet. 1987 Oct;28(2):367-71. doi: 10.1016/0165-4608(87)90226-3.
We present a case of refractory anemia with monosomy 2 in the 41 cells of the bone marrow studied and a double minute chromosome (dmin) in 68% of these cells. The illness developed over a period of 3 years and the patient died of cerebral hemorrhage without developing leukemia.
我们报告一例难治性贫血患者,在所研究的41个骨髓细胞中有2号染色体单体,且68%的这些细胞中存在双微体染色体(dmin)。病程长达3年,患者死于脑出血,未发展为白血病。