Send Thorsten, Jansen Christian, Eichhorn Klaus W, Bieber Thomas, Hornung Thorsten
Klinik für Hals-Nasen-Ohrenheilkunde, Universitätsklinikum Bonn.
Klinik für Medizinische Klinik und Poliklinik I, Universitätsklinikum Bonn.
Laryngorhinootologie. 2022 Jul;101(7):585-591. doi: 10.1055/a-1550-2904. Epub 2021 Nov 11.
Sarcoidosis is a granulomatous multisystem disease of unknown etiology and relatively rare. The heterogeneous clinical picture is a diagnostic challenge. We are investigating whether the superficially visible cutaneous lesions can lead to the differential diagnosis of sarcoidosis and what systemic manifestations are present.
As part of our exploratory retrospective investigation (eight years) a total of 32 patients with cutaneous sarcoidosis were identified and analyzed.
In many cases the dermatologists considered the differential diagnosis of sarcoidosis even before biopsy (71.8%); in our previous study with ENT-patients the diagnosis wasn't considered in a single case by the attending doctors at this time and without any prevoius suspicion. Sarcoidosis of the skin in the head and neck area is the second most common cutaneous manifestation. After biopsy (Gold standard) the search for further possible organ manifestations is essential (e.g. lungs, heart) to treat them in an early stage and to prevent complications of a possible chronic course (including cardiac arrhythmias, pulmonary fibrosis).
结节病是一种病因不明的肉芽肿性多系统疾病，相对罕见。其临床表现多样，这给诊断带来了挑战。我们正在研究表面可见的皮肤病变是否有助于结节病的鉴别诊断以及存在哪些全身表现。
作为我们探索性回顾性研究（八年）的一部分，共确定并分析了32例皮肤结节病患者。
在许多病例中，皮肤科医生甚至在活检前就考虑了结节病的鉴别诊断（71.8%）；在我们之前对耳鼻喉科患者的研究中，主治医生当时在没有任何先前怀疑的情况下，没有一例考虑到该诊断。头颈部皮肤结节病是第二常见的皮肤表现。活检（金标准）后，寻找其他可能的器官表现（如肺部、心脏）至关重要，以便在早期进行治疗并预防可能的慢性病程并发症（包括心律失常、肺纤维化）。
