Department of Ophthalmology, Southwest Hospital/Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, China; Key Laboratory of Visual Damage and Regeneration and Restoration of Chongqing, Chongqing, China.
Ann Palliat Med. 2021 Oct;10(10):10922-10929. doi: 10.21037/apm-21-2554.
To investigate the clinical safety and efficacy of foldable capsular vitreous body (FCVB) in the treatment of severe silicone oil-dependent eyes.
Five patients (5 eyes) of severe silicone oil-dependent eyes underwent FCVB implantation from December 2019 to July 2020. The preoperative and postoperative visual acuity, intraocular pressure, corneal conditions, postoperative retinal reattachment, and FCVB status were observed. The patients were followed up for 12-15 months.
A total of 5 patients (5 eyes) with severe silicone oil-dependent eyes were included, including 3 males and 2 females, with an average age of 32±14 years. The longest silicone oil tamponade time was 8 years, and the shortest was 2 years, with an average of 5±3 years. All patients were safely and successfully implanted with FCVB without severe intraoperative or postoperative complications. Up to the last follow-up, there was no significant change between preoperative and postoperative visual acuity. Before surgery, 4 patients had normal intraocular pressure while 1 patient had ocular hypotension; after surgery, the latter was still at a low level, and the other patients had intraocular pressure in the normal range.
The FCVB is a safe, feasible, and effective vitreous substitute to maintain ocular morphology and intraocular pressure without aggravating silicone oil emulsification, retinal displacement, or corneal degeneration during the implantation period of 12-15 months.
研究折叠式囊袋玻璃体（FCVB）治疗严重硅油依赖眼的临床安全性和疗效。
2019 年 12 月至 2020 年 7 月，5 例（5 眼）严重硅油依赖眼患者行 FCVB 植入术。观察术前、术后视力、眼压、角膜情况、术后视网膜复位及 FCVB 情况。患者随访 12-15 个月。
共纳入 5 例（5 眼）严重硅油依赖眼患者，男 3 例，女 2 例，平均年龄 32±14 岁。最长硅油填充时间 8 年，最短 2 年，平均 5±3 年。所有患者均安全、顺利植入 FCVB，无严重术中、术后并发症。至末次随访时，视力较术前无明显变化。术前 4 例眼压正常，1 例眼压偏低；术后后者仍偏低，其余患者眼压均在正常范围内。
FCVB 是一种安全、可行、有效的玻璃体替代物，在 12-15 个月的植入期内，不会加重硅油乳化、视网膜脱离或角膜变性，能维持眼球形态和眼压。
