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折叠式囊袋玻璃体植入物填充轻或重硅油治疗硅油依赖眼的疗效。

Efficacy of Foldable Capsular Vitreous Body Implants Filled With Light or Heavy Silicone Oil in the Treatment of Silicone Oil-dependent Eyes.

机构信息

Department of ophthalmology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

出版信息

Transl Vis Sci Technol. 2024 Sep 3;13(9):2. doi: 10.1167/tvst.13.9.2.

Abstract

PURPOSE

The purpose of this study was to compare the clinical efficacy of foldable capsular vitreous body (FCVB) filled with either light or heavy silicone oil and the incidence of complications after their implantation for the treatment of severe ocular trauma and silicone oil-dependent eyes.

METHODS

FCVB filled with either light (n = 16) or heavy (n = 8) silicone oil was implanted in 24 patients. During the 12-month follow-up period, the intraocular pressure, final best-corrected visual acuity, retinal reattachment condition, position of the FCVB, and complications were assessed.

RESULTS

All surgeries were performed without issue. There was no significant difference in preoperative and postoperative best-corrected visual acuity between the two groups. A significant improvement in the intraocular pressure was observed after surgery in both the light silicone oil (P = 0.029) and heavy silicone oil (P = 0.035) groups. None of the patients developed displacement or prolapse of the FCVB. The most common early and late postoperative complications were postoperative hemorrhage (33.3%) and corneal opacification (50%), respectively.

CONCLUSIONS

FCVB filled with heavy silicone oil can be used as a supplemental therapy for patients who have lost the anterior segment of their eye, have lesions of the inferior retina, or cannot maintain the prone position for various reasons.

TRANSLATIONAL RELEVANCE

Implantation of FCVB combined with heavy silicone oil compensates for the shortcomings of this with light silicone oil, providing patients with more personalized treatment.

摘要

目的

本研究旨在比较填充轻比重硅油和重比重硅油的折叠式囊袋玻璃体(FCVB)在治疗严重眼外伤和硅油依赖眼中的临床疗效及并发症发生率。

方法

将 FCVB 分别填充轻比重硅油(n=16)和重比重硅油(n=8),并将其植入 24 例患者。在 12 个月的随访期间,评估眼内压、最终最佳矫正视力、视网膜复位情况、FCVB 位置和并发症。

结果

所有手术均顺利完成。两组患者术前和术后最佳矫正视力无显著差异。两组患者术后眼压均明显改善(轻硅油组:P=0.029;重硅油组:P=0.035)。无一例 FCVB 发生移位或脱出。最常见的早期和晚期术后并发症分别为术后出血(33.3%)和角膜混浊(50%)。

结论

对于眼球前段缺失、下视网膜病变或因各种原因无法保持俯卧位的患者,填充重比重硅油的 FCVB 可作为一种补充治疗方法。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5984/11373723/2e553c193bb7/tvst-13-9-2-f001.jpg

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